Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 4920299..4920705 Replicon chromosome
Accession NZ_CP066945
Organism Xanthomonas campestris pv. campestris strain 08284

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH306_RS21370 Protein ID WP_274376545.1
Coordinates 4920550..4920705 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH306_RS21365 Protein ID WP_274376544.1
Coordinates 4920299..4920553 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH306_RS21340 (JH306_21265) 4915801..4916640 + 840 WP_014509612.1 SDR family oxidoreductase -
JH306_RS21345 (JH306_21270) 4916784..4918049 + 1266 WP_040942139.1 phospholipase D-like domain-containing protein -
JH306_RS21350 (JH306_21275) 4918081..4918596 - 516 WP_040942140.1 hypothetical protein -
JH306_RS21355 (JH306_21280) 4918853..4919059 + 207 WP_014509615.1 hypothetical protein -
JH306_RS21360 (JH306_21285) 4919046..4920161 + 1116 WP_012439694.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH306_RS21365 (JH306_21290) 4920299..4920553 + 255 WP_274376544.1 Arc family DNA-binding protein Antitoxin
JH306_RS21370 (JH306_21295) 4920550..4920705 + 156 WP_274376545.1 hypothetical protein Toxin
JH306_RS21375 (JH306_21300) 4920762..4921730 - 969 WP_274376546.1 DUF2971 domain-containing protein -
JH306_RS21385 (JH306_21310) 4923077..4924543 + 1467 Protein_4126 alpha/beta hydrolase-fold protein -
JH306_RS21390 (JH306_21315) 4925267..4925668 - 402 WP_016945062.1 DUF2384 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(1-46)


Sequences


Toxin        


Download         Length: 52 a.a.        Molecular weight: 5653.58 Da        Isoelectric Point: 4.3220

>T185482 WP_274376545.1 NZ_CP066945:4920550-4920705 [Xanthomonas campestris pv. campestris]
VTLLDTNVIFGPNLHVVAWIDAQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185482 NZ_CP088265:1474995-1475363 [Leclercia sp. G3L]
ATGACCCTGCAATTTATCTCAGCGGAAGAGATAGTCCTGTTTCATGACAAACTCCTCAGCGTCACGCCTGGCGTCGCGGG
AATGTCGGATCCGGGTCGTGCTGAAGCGCTGCTCTATCGCGTGTTAAACAAATATCAATACGAAGGGGTGACCGATGTCT
GGATCCTGGCGGCGATGCATTTGCTGGCCATCTCCCGCGGCCATATCTTCAATGATGGTAATAAACGCACGGCATTGTTT
ATCACCTTGCTTTTCCTCAAACGTAACGGCATTTCGCTGAAGGCCAATCCGGATTATGTGGCGATGACGGTTGAGGCTGC
TGCGGGCCGTCTGTCGCTTGAAGAAATTGTGGAGCGTTTACGCCGCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8940.38 Da        Isoelectric Point: 10.8780

>AT185482 WP_274376544.1 NZ_CP066945:4920299-4920553 [Xanthomonas campestris pv. campestris]
MPSFTVRNIPEDVHRAIRARAAQHGRSTEAEIRAILESAAKPAGQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185482 NZ_CP088265:1474777-1474998 [Leclercia sp. G3L]
ATGCGTACAATGAACTATAGCGAAGCACGTCAGAATCTTGCCTCAGCGCTGGATTCTGCCGCGACGGGAACACCCGTCAC
CATCACGCGTCGCGGTCATAAACCTGCCGTGATTATCAGCGCAGAAGAATTTGAACGTTATCAGGTGGCAAAACTGGATG
CCGAGTTTGACGCCATTATGGGTATTCATGGCAACGAAATTAGGGAACTGGCTGACAAATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References