185481

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4583866..4584229 Replicon chromosome
Accession NZ_CP066945
Organism Xanthomonas campestris pv. campestris strain 08284

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH306_RS19980 Protein ID WP_011270059.1
Coordinates 4583866..4584000 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH306_RS19985 Protein ID WP_011038999.1
Coordinates 4584077..4584229 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH306_RS19960 (JH306_19885) 4579130..4580782 - 1653 WP_043877841.1 M28 family metallopeptidase -
JH306_RS19965 (JH306_19890) 4580947..4581891 - 945 WP_068574725.1 MBL fold metallo-hydrolase -
JH306_RS19970 (JH306_19895) 4581975..4583264 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
JH306_RS19975 (JH306_19900) 4583424..4583633 - 210 WP_011038998.1 CsbD family protein -
JH306_RS19980 (JH306_19905) 4583866..4584000 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH306_RS19985 (JH306_19910) 4584077..4584229 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH306_RS19990 (JH306_19915) 4584340..4585263 - 924 WP_011039000.1 arginase -
JH306_RS19995 (JH306_19920) 4585577..4586038 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JH306_RS20000 (JH306_19925) 4586121..4586480 + 360 WP_011039002.1 hypothetical protein -
JH306_RS20005 (JH306_19930) 4586583..4587500 + 918 WP_012439506.1 hypothetical protein -
JH306_RS20010 (JH306_19935) 4587497..4588039 + 543 WP_012439507.1 GTPase -
JH306_RS20015 (JH306_19940) 4588374..4589057 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185481 WP_011270059.1 NZ_CP066945:c4584000-4583866 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185481 NZ_CP088265:1220935-1221249 [Leclercia sp. G3L]
ATGCTATTCATTGAAACGGATATCTTCACTGAAGACGTCAAAAAATTACTGGATGACGACGAATACCATAAACTGCAGGT
CTTTCTGGCAATGCAGCCTGAATATGGCGATCTGATTCAGAACACGGGAGGCTTACGCAAGATTCGCTGGCTTGCCGGCG
GTAAGGGAGGAAAGCGTAGTGGTGTACGAGTCATTTATTCTTATCGCTCACGTGAAAATGAAATTCGATTGCTGCTCATC
TATCGCAAAGGGATCAAAGATGACCTGTCAGCAAATGAGAAAGCCGTACTGAAAATGATTATTGAGAGGTGGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185481 WP_011038999.1 NZ_CP066945:c4584229-4584077 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185481 NZ_CP088265:1221250-1221540 [Leclercia sp. G3L]
ATGGATAAGGCGCTATTTGAGCGGTTAACTCAAAGCGTGGCTCAGATGAACGAAATTGCCGGGGGCAAACGCGAGCCATC
GCGCACCTTTCAAATCGATGCCATGAAAATTAAAGAAATTCGTCAGGCGTCAGGGCTGTCGCAAAGTAAATTCGCGCAAC
TAATCTCGGTCAGTGTTGATACGCTACGCAACTGGGAGCAAGGTAGACGTTCACCTACAGGCCCGGCCAAGGCGCTACTT
CGTGCTATTGCCAACGATCCGCAGCATGTTATTCCTGCGCTATCCCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References