Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
| Location | 1217099..1217877 | Replicon | chromosome |
| Accession | NZ_CP066943 | ||
| Organism | Xanthomonas campestris pv. campestris strain 12049 | ||
Toxin (Protein)
| Gene name | TacT2 | Uniprot ID | Q8P667 |
| Locus tag | JH293_RS05100 | Protein ID | WP_011038220.1 |
| Coordinates | 1217099..1217590 (-) | Length | 164 a.a. |
Antitoxin (Protein)
| Gene name | TacA2 | Uniprot ID | Q8P668 |
| Locus tag | JH293_RS05105 | Protein ID | WP_011038219.1 |
| Coordinates | 1217587..1217877 (-) | Length | 97 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JH293_RS05085 (JH293_05090) | 1213427..1214302 | + | 876 | WP_016945000.1 | 30S ribosomal protein S6--L-glutamate ligase | - |
| JH293_RS05090 (JH293_05095) | 1214952..1215629 | + | 678 | WP_003490678.1 | response regulator transcription factor | - |
| JH293_RS05095 (JH293_05100) | 1215622..1216956 | + | 1335 | WP_057671653.1 | HAMP domain-containing sensor histidine kinase | - |
| JH293_RS05100 (JH293_05105) | 1217099..1217590 | - | 492 | WP_011038220.1 | GNAT family N-acetyltransferase | Toxin |
| JH293_RS05105 (JH293_05110) | 1217587..1217877 | - | 291 | WP_011038219.1 | DUF1778 domain-containing protein | Antitoxin |
| JH293_RS05110 (JH293_05115) | 1217952..1218353 | - | 402 | WP_040940795.1 | SymE family type I addiction module toxin | - |
| JH293_RS05115 (JH293_05120) | 1218885..1219508 | - | 624 | WP_011038217.1 | dephospho-CoA kinase | - |
| JH293_RS05120 (JH293_05125) | 1219522..1220385 | - | 864 | WP_011038216.1 | A24 family peptidase | - |
| JH293_RS05125 (JH293_05130) | 1220392..1221648 | - | 1257 | WP_011038215.1 | type II secretion system F family protein | - |
| JH293_RS05130 (JH293_05135) | 1221975..1222415 | + | 441 | WP_011038214.1 | pilin | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 1147706..1238572 | 90866 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 164 a.a. Molecular weight: 17638.31 Da Isoelectric Point: 8.1192
>T185479 WP_011038220.1 NZ_CP066943:c1217590-1217099 [Xanthomonas campestris pv. campestris]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL
Download Length: 492 bp
>T185479 NZ_CP088265:611343-611918 [Leclercia sp. G3L]
ATGACACACTCACCCTATCCCGTCGTTCTTGATGCCTGCGTGCTATACCCATCAATGCTGCGGGATCTTCTCATGCACAT
TGGGAAGACTGGCTTATATCAGCCCAAATGGACTACTCAGATACACGATGAATGGCAGCGTAATCTGCTTATTAATCGCC
CTGATATCACCGCAGACCAGCTGAAGCGCACCGAAATGCTAATGAATAAAGCCTTCGGCGACGCCTGCGTATCAGGGTAT
GAGAGTATTATTGATGGCCTTAGCCTGCCGGATCAGGATGACAGGCATGTGCTTGCCGCGGCGATTCGTTCGGATTCCGA
AGTGATTGTAACCTACAATCTTGTCGATTTTCCCGGCGGAAACCTGGCTGAATTTGATGTTGAAGCGCTCCACCCGGATG
AGTTCTTATCAGACCTTTTTGACCTGAACCATGCGCTGGTTCTCGAGGCGGTGAGAATGCAGCGATCGCACCTGCGTCAT
CCTCCCCTCAACCCAGACCAATTTTTGCAAGGCCTGCTGCAACTGGGCTTGCCGAAAACAGTGACTGAGCTGGAAAAATA
CAGAGTAATGATTTAG
ATGACACACTCACCCTATCCCGTCGTTCTTGATGCCTGCGTGCTATACCCATCAATGCTGCGGGATCTTCTCATGCACAT
TGGGAAGACTGGCTTATATCAGCCCAAATGGACTACTCAGATACACGATGAATGGCAGCGTAATCTGCTTATTAATCGCC
CTGATATCACCGCAGACCAGCTGAAGCGCACCGAAATGCTAATGAATAAAGCCTTCGGCGACGCCTGCGTATCAGGGTAT
GAGAGTATTATTGATGGCCTTAGCCTGCCGGATCAGGATGACAGGCATGTGCTTGCCGCGGCGATTCGTTCGGATTCCGA
AGTGATTGTAACCTACAATCTTGTCGATTTTCCCGGCGGAAACCTGGCTGAATTTGATGTTGAAGCGCTCCACCCGGATG
AGTTCTTATCAGACCTTTTTGACCTGAACCATGCGCTGGTTCTCGAGGCGGTGAGAATGCAGCGATCGCACCTGCGTCAT
CCTCCCCTCAACCCAGACCAATTTTTGCAAGGCCTGCTGCAACTGGGCTTGCCGAAAACAGTGACTGAGCTGGAAAAATA
CAGAGTAATGATTTAG
Antitoxin
Download Length: 97 a.a. Molecular weight: 10678.23 Da Isoelectric Point: 10.5480
>AT185479 WP_011038219.1 NZ_CP066943:c1217877-1217587 [Xanthomonas campestris pv. campestris]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA
Download Length: 291 bp
>AT185479 NZ_CP088265:610882-611343 [Leclercia sp. G3L]
ATGACAAACTCACTTCTGAACAGCCTTACGTTACCGGCTCCAAAGGAGATTGAGGCAGCTGTACGCGGACAAAGGGAGCT
TGCTACGTTTCTGTCCACAAAGCAGGAAACGCAGAAAATTACGATTCAGGATGCACAGGATGTGACCCATCAAATAGAGC
TTCCAACCTCTTCTCTGACGCTTCTGATGAGTATCCTCGGTGAACTGGCTGCGGGCAATGCCGTCCAGGTTGTGCCCGTG
CATGCTGAATTAACGACGCAGGAAGCTGCCAACATCCTGAACGTTTCGCGCCCACATATGGTGAAACTTCTGGAGGAAGG
AAAGCTACCTTTCCATAAAACTGGCCGTCATCGCCGCATTCTTTTTGCAGACTTGATGAAGTACAAAGATCAGCGTGATG
CAGAAAGCATACAAGCCCTTCGCGAGCTGGCGGAACAAAGTCAGGAGCTTGGATTTTACTGA
ATGACAAACTCACTTCTGAACAGCCTTACGTTACCGGCTCCAAAGGAGATTGAGGCAGCTGTACGCGGACAAAGGGAGCT
TGCTACGTTTCTGTCCACAAAGCAGGAAACGCAGAAAATTACGATTCAGGATGCACAGGATGTGACCCATCAAATAGAGC
TTCCAACCTCTTCTCTGACGCTTCTGATGAGTATCCTCGGTGAACTGGCTGCGGGCAATGCCGTCCAGGTTGTGCCCGTG
CATGCTGAATTAACGACGCAGGAAGCTGCCAACATCCTGAACGTTTCGCGCCCACATATGGTGAAACTTCTGGAGGAAGG
AAAGCTACCTTTCCATAAAACTGGCCGTCATCGCCGCATTCTTTTTGCAGACTTGATGAAGTACAAAGATCAGCGTGATG
CAGAAAGCATACAAGCCCTTCGCGAGCTGGCGGAACAAAGTCAGGAGCTTGGATTTTACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|