185476

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 427734..428097 Replicon chromosome
Accession NZ_CP066939
Organism Xanthomonas campestris pv. campestris strain 12112

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH286_RS01725 Protein ID WP_011270059.1
Coordinates 427963..428097 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH286_RS01720 Protein ID WP_011038999.1
Coordinates 427734..427886 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH286_RS01690 (JH286_01690) 422905..423588 - 684 WP_050911792.1 dTMP kinase -
JH286_RS01695 (JH286_01695) 423924..424466 - 543 WP_068574727.1 GTPase -
JH286_RS01700 (JH286_01700) 424463..425380 - 918 WP_014506231.1 hypothetical protein -
JH286_RS01705 (JH286_01705) 425483..425842 - 360 WP_011039002.1 hypothetical protein -
JH286_RS01710 (JH286_01710) 425925..426386 - 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JH286_RS01715 (JH286_01715) 426700..427623 + 924 WP_011039000.1 arginase -
JH286_RS01720 (JH286_01720) 427734..427886 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH286_RS01725 (JH286_01725) 427963..428097 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH286_RS01730 (JH286_01730) 428330..428539 + 210 WP_011038998.1 CsbD family protein -
JH286_RS01735 (JH286_01735) 428699..429988 + 1290 WP_029629069.1 tryptophan--tRNA ligase -
JH286_RS01740 (JH286_01740) 430072..431016 + 945 WP_068574725.1 MBL fold metallo-hydrolase -
JH286_RS01745 (JH286_01745) 431181..432833 + 1653 WP_043877841.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185476 WP_011270059.1 NZ_CP066939:427963-428097 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185476 NZ_CP088265:62055-62273 [Leclercia sp. G3L]
ATGTCTGATAAACCATTAACCAAGACAGATTATTTGATGCGTTTGCGACGCTGTCAGTCAATTGACACCCTTGAACGTGT
GATTGAGAAAAATAAATACGAGCTTTCTGATAATGAGTTAGCGGTATTCTATTCCGCAGCGGATCATCGCCTGGCTGAAC
TTACGATGAATAAGCTGTACGATAAAATTCCTACCGCCGTGTGGAAATTCGTACGCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185476 WP_011038999.1 NZ_CP066939:427734-427886 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185476 NZ_CP088265:61654-62046 [Leclercia sp. G3L]
ATGGACGAATACTCGCCCAAAAGGCAAGATATTGCACAGTTGAAATTCCTTTGTGAATCCCTGTACCATGACTGCCTTTC
CAATCTCGATGAAAGCAACCATGGCTGGGTCAATGACCCTACTTCTGCCATTAATTTGCAGCTAAACGAGTTGATTGAGC
ATATAGCAACCTTCGCCCTTAATTATAAAATTAAGTATAACGAAGATAATAAGTTGATTGAGCAAATTGACGGATACCTG
GATGACACTTTTATGTTATTCAGCAGCTACGGCATTAACGCGCAGGATTTGCAGAAATGGCGTAAATCGGGCAATCGGCT
TTTTCGTTGTTTTGTCAATGCAAGCAGGGCTAACCCGTTAGCTTCTCCGGTTAAAATTATTACAAACAATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References