Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 4966371..4966777 Replicon chromosome
Accession NZ_CP066937
Organism Xanthomonas campestris pv. campestris strain 13108G

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH313_RS21555 Protein ID WP_267129426.1
Coordinates 4966622..4966777 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH313_RS21550 Protein ID WP_070697976.1
Coordinates 4966371..4966625 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH313_RS21525 (JH313_21490) 4961870..4962709 + 840 WP_014509612.1 SDR family oxidoreductase -
JH313_RS21530 (JH313_21495) 4962853..4964118 + 1266 WP_043877851.1 phospholipase D-like domain-containing protein -
JH313_RS21535 (JH313_21500) 4964136..4964665 - 530 Protein_4154 hypothetical protein -
JH313_RS21540 (JH313_21505) 4964924..4965130 + 207 WP_014509615.1 hypothetical protein -
JH313_RS21545 (JH313_21510) 4965117..4966232 + 1116 WP_050912541.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH313_RS21550 (JH313_21515) 4966371..4966625 + 255 WP_070697976.1 Arc family DNA-binding protein Antitoxin
JH313_RS21555 (JH313_21520) 4966622..4966777 + 156 WP_267129426.1 hypothetical protein Toxin
JH313_RS21560 (JH313_21525) 4966822..4968189 - 1368 WP_011035783.1 IS5-like element IS1478 family transposase -
JH313_RS21565 (JH313_21530) 4968449..4969306 - 858 WP_012439703.1 SIR2 family protein -
JH313_RS21570 (JH313_21535) 4969308..4970327 - 1020 WP_011039254.1 AAA family ATPase -
JH313_RS21575 (JH313_21540) 4970510..4970662 - 153 Protein_4162 topoisomerase DNA-binding C4 zinc finger domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(1-39)


Sequences


Toxin        


Download         Length: 52 a.a.        Molecular weight: 5681.63 Da        Isoelectric Point: 4.3220

>T185475 WP_267129426.1 NZ_CP066937:4966622-4966777 [Xanthomonas campestris pv. campestris]
VTLLDTNVIFGPNLHVVAWIDVQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185475 NZ_CP088263:c81664-81254 [Leclercia sp. G3L]
GTGAAGAAGACCTATATGCTCGACACCGGGATCTGCGCGCTTATCCTGCGCGAACAGCCGGCAGCTTTACTTAAGCGCCT
GGAGCAGGCGGTCCTGGACGGCGATCGGATTGTGGTTTCCGCCATCACCTGGGCCGAAATTTCTCTGGCCGCCCGGGCGT
CAGGCCCTGCCACTCAGCAGCTGGCGGATGCCTTTGCCGCCCGGCTCGATGCCATCCTGCCCTGGGACCGCGCCGCAGTG
GACGCCACCACGGACGTTAAGGTGGCGCTGCGCCTCGCCGGGACGCCGATCGGCCTTAACGACACGGCGATTGCGGGGCA
TGCCATTGCCGCCGGCGCCGTCCTGGTGACGGGGAAGGGGGGAGAGTTTGAGCGGGTGCCGGGCCTGACGCTGGAAGAAT
GCCTTAGCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9056.45 Da        Isoelectric Point: 10.4748

>AT185475 WP_070697976.1 NZ_CP066937:4966371-4966625 [Xanthomonas campestris pv. campestris]
MPSFTVRNIPEDVHRAIWARAAQHGRSTEAEIRAILESAARPADQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185475 NZ_CP088263:c81891-81661 [Leclercia sp. G3L]
ATGAGAACCGTATCCATTTTTAAAAATGGCAACAACCGCGCCATCCGTCTGCCCCGCGATCTGGATTTTGAGGGGGTAAG
CGAGCTGGAGATCGTCCGGGAAGGAGACAGCATCATCCTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGATGG
AAAAAGCAGACCCGGACTTTATGGCAGAGCGTGAGGACGTTATCAGCGACGAAGGACGTTTTGAACTGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References