185474

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4627149..4627512 Replicon chromosome
Accession NZ_CP066937
Organism Xanthomonas campestris pv. campestris strain 13108G

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH313_RS20150 Protein ID WP_011270059.1
Coordinates 4627149..4627283 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH313_RS20155 Protein ID WP_011038999.1
Coordinates 4627360..4627512 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH313_RS20130 (JH313_20105) 4622413..4624065 - 1653 WP_050912502.1 M28 family metallopeptidase -
JH313_RS20135 (JH313_20110) 4624230..4625174 - 945 WP_043877842.1 MBL fold metallo-hydrolase -
JH313_RS20140 (JH313_20115) 4625258..4626547 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
JH313_RS20145 (JH313_20120) 4626707..4626916 - 210 WP_011038998.1 CsbD family protein -
JH313_RS20150 (JH313_20125) 4627149..4627283 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH313_RS20155 (JH313_20130) 4627360..4627512 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH313_RS20160 (JH313_20135) 4627623..4628546 - 924 Protein_3890 arginase -
JH313_RS20165 (JH313_20140) 4628860..4629321 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JH313_RS20170 (JH313_20145) 4629404..4629763 + 360 WP_011039002.1 hypothetical protein -
JH313_RS20175 (JH313_20150) 4629866..4630783 + 918 WP_011039003.1 hypothetical protein -
JH313_RS20180 (JH313_20155) 4630780..4631322 + 543 WP_011039004.1 GTPase -
JH313_RS20185 (JH313_20160) 4631657..4632340 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185474 WP_011270059.1 NZ_CP066937:c4627283-4627149 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185474 NZ_CP088263:c76122-75706 [Leclercia sp. G3L]
ATGAAGAAAACCTGGATGCTCGACACCAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGCAGCGGTGCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGTGATCGCATTGTGGTCTCGGCCGTGACGTATGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCATATTCAGCTGGTCGACGCGTTCTGCGCGCGCCTCGATGCCGTCCTGCCCTGGGACCGCGCC
GCGGTGGACGCCACGACGGACATCCGGGTGGCGCTGCGCCTAGCCGGGACGCCGATCGGCCCGAATGACACGGCCATTGC
CGGGCACGCCATCGCGGCGGGCGCCATCCTGGTGACGAACAATGTGAGAGAGTTTGCGCGGGTCCCGGGCCTGGTGCTGG
AAGACTGGGTGAAATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185474 WP_011038999.1 NZ_CP066937:c4627512-4627360 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185474 NZ_CP088263:c76349-76119 [Leclercia sp. G3L]
ATGCGCACAGTTTCGATATTTAAAAACGGCAATAACCGCGCCATCCGTCTGCCCCGGGACCTGGATTTTGATGGCGTCAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGCTGG
ACAGGGCCGATCCGGACTTTATGGCGGAGCGTGAGGATGTGGTCAGCGATGAAGGACGCTTTGAGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References