Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 5035793..5036199 Replicon chromosome
Accession NZ_CP066934
Organism Xanthomonas campestris pv. campestris strain 08290

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH256_RS21880 Protein ID WP_267129426.1
Coordinates 5036044..5036199 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH256_RS21875 Protein ID WP_070694028.1
Coordinates 5035793..5036047 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH256_RS21850 (JH256_21790) 5031294..5032133 + 840 WP_014509612.1 SDR family oxidoreductase -
JH256_RS21855 (JH256_21795) 5032277..5033542 + 1266 WP_040942139.1 phospholipase D-like domain-containing protein -
JH256_RS21860 (JH256_21800) 5033574..5034089 - 516 WP_070694020.1 hypothetical protein -
JH256_RS21865 (JH256_21805) 5034346..5034552 + 207 WP_070694021.1 hypothetical protein -
JH256_RS21870 (JH256_21810) 5034539..5035654 + 1116 WP_070694026.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH256_RS21875 (JH256_21815) 5035793..5036047 + 255 WP_070694028.1 Arc family DNA-binding protein Antitoxin
JH256_RS21880 (JH256_21820) 5036044..5036199 + 156 WP_267129426.1 hypothetical protein Toxin
JH256_RS21885 (JH256_21825) 5036254..5037225 - 972 WP_081390822.1 DUF2971 domain-containing protein -
JH256_RS21890 (JH256_21830) 5037384..5038790 + 1407 Protein_4227 alpha/beta hydrolase-fold protein -
JH256_RS21900 (JH256_21840) 5040025..5040240 + 216 Protein_4229 enterochelin esterase -
JH256_RS21905 (JH256_21845) 5040511..5040912 - 402 WP_162277263.1 DUF2384 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5035793..5048155 12362


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5681.63 Da        Isoelectric Point: 4.3220

>T185470 WP_267129426.1 NZ_CP066934:5036044-5036199 [Xanthomonas campestris pv. campestris]
VTLLDTNVIFGPNLHVVAWIDVQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185470 NZ_CP088247:801409-801834 [Methylorubrum sp. B1-46]
GTGATCGTCCTCGACACCAACGTCCTGTCCGAGCTGTGGCGGGCCACGCCCGATCCCGGCGTGCTGACCTGGGTCGATGC
GCAGGCGGTCGAGACCCTCTACCTCACCGCCGTCACGGTCGCAGAACTCCGCTTCGGCTTGGCTACGATGCCGGCGGACA
AACGGCGCGACATCTTTCGCGATCGGCTGGAGCGCGAAGTGCTTCCGGCCTTCGCGGGCCGCGTGCTGCCGTTCGATCTC
GACGCGTCGCGCCACTACGCCGCCTTCATGGCGCGCGCCCGCGCCGCGGGGAAGGCCATCGGCATGGCGGACGGCACCAT
CGCCGCCACCGCCGCGGTTCGGGGCTTCATCGTCGCGACACGGGATACCGGTCCATTCGAAGCAACCGGGATCGGCGTGA
TCAATCCCTGGCGAACCGCGGGTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9028.44 Da        Isoelectric Point: 10.3861

>AT185470 WP_070694028.1 NZ_CP066934:5035793-5036047 [Xanthomonas campestris pv. campestris]
MPSFTVRNIPEDVHRAIWARAAQHGRSTEAEIRAILESAAKPADQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185470 NZ_CP088247:801155-801412 [Methylorubrum sp. B1-46]
ATGGCGTCGATTACCATCCGCAACGTGCCCGACGAGGTGCATCGCGCCCTGCGCATCCGTGCCGCGCAGCACGGGCGCAG
CACCGAAGCCGAAATCCGCGCCATCCTGGAACAGGCGGCCAAGCCGGCCGGCCGGATGAAGCTCGGCTCGCTCCTGTCCT
CCATCGCCCGCGACGCCGGCGGCCTGACCGAGGCGGAAGCCGATGCCTTCGATCGGTTTCGCGACAGGGCGCCGGCCGAA
CCGATGCGGTTCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References