Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4704456..4704819 Replicon chromosome
Accession NZ_CP066934
Organism Xanthomonas campestris pv. campestris strain 08290

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH256_RS20530 Protein ID WP_011270059.1
Coordinates 4704456..4704590 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH256_RS20535 Protein ID WP_011038999.1
Coordinates 4704667..4704819 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH256_RS20510 (JH256_20450) 4699720..4701372 - 1653 WP_043877841.1 M28 family metallopeptidase -
JH256_RS20515 (JH256_20455) 4701537..4702481 - 945 WP_068574725.1 MBL fold metallo-hydrolase -
JH256_RS20520 (JH256_20460) 4702565..4703854 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
JH256_RS20525 (JH256_20465) 4704014..4704223 - 210 WP_011038998.1 CsbD family protein -
JH256_RS20530 (JH256_20470) 4704456..4704590 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH256_RS20535 (JH256_20475) 4704667..4704819 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH256_RS20540 (JH256_20480) 4704930..4705853 - 924 WP_011039000.1 arginase -
JH256_RS20545 (JH256_20485) 4706167..4706628 + 462 WP_042595651.1 roadblock/LC7 domain-containing protein -
JH256_RS20550 (JH256_20490) 4706711..4707070 + 360 WP_011039002.1 hypothetical protein -
JH256_RS20555 (JH256_20495) 4707173..4708090 + 918 WP_057673531.1 hypothetical protein -
JH256_RS20560 (JH256_20500) 4708087..4708629 + 543 WP_057673534.1 GTPase -
JH256_RS20565 (JH256_20505) 4708965..4709648 + 684 WP_050911792.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185469 WP_011270059.1 NZ_CP066934:c4704590-4704456 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185469 NZ_CP088247:c228972-227659 [Methylorubrum sp. B1-46]
GTGACCGTCGCCACCGTCCGCCTCTGGGGCACCGACATCGGTGCCGTCTCGCTCGACGCCCAAGGTGGCGTCGCCGCCTT
CCAGTACGACCCCGACTTCGTCGCCGCTCCAATCGACGTCGAGCTCTCCCCATTCAAGATGCCGCGCGGGGAGGCGCCGT
TCTCGTTTCCCGAACTCGACCGGAAGGCATTCCACGGGCTGCCGGGCATGCTCGCGGACAGCCTGCCCGATAAGTACGGC
AACGCCGTCATCGACGCGTGGCTCGCCTCGCAGGGCCGCGCCCCGGAAAGCTTCGACGCCGTCGAGCGCCTCTGCTACAT
CGGAACCCGCGGCATGGGCGCCCTGGAGTTCGCGCCTGTGAAGGGACCCTCTTCAGGCAAGTCGCAGACCGTCCACCTCG
ATGCGCTCGTCCAGCTCGCCTCCGACGTGCTCTCCAATCGCGCGGCTCTGGCCCAATCGTTCGCGGAAGGGTCGCGCGAG
GCCGCGCTGCGCGAGATCCTGCTCATCGGGACCTCGGCCGGCGGAGCCCGGGCCAAGGCGGTCATTGCCTGGAACCCGGA
CACGAACGAAGTGCGATCGGGCCAAGCCGTGGCCGAGCCGGGCTTCGGCTACTGGCTCCTGAAGTTCGACGGTGTGGCCG
GCAACGGCGACAAGGACCTGCGCGACCCGCAAGGCTACGGGGCCATCGAGTACGCCTACTCGTTGATGGCCCAGGCGGCG
GGCGTCGCCATGGGCGACACCCGCATCCTCGAGGAGAACGGACGGCGGCACTTCATGACCCGCCGCTTCGACCGGGAGGA
CGGCGGCGGCAAGCTGCACATGCAGTCGCTGGCGGCGTTGGCGCACCTCGACTTCAACCAGCCGCGCACGCACTCCTACG
ACCAAGCGTTCCTCGCCATCCGACAACTCGATCTCGGCATGGACGCGGTCGAGGAGCAATTCCGCCGGATGGCCTTCAAC
GTCGTCGGGCGTAACCAGGACGACCACGTCAAGAACATCGCCTTCCTGATGGATCGAGACGGCACGTGGAGCCTGTCCCC
AGCCTACGACATCACGTGGTCGTACAACCCGCTCGGGGACTGGACCTCGAAGCACCAGATGTCGGTCAACGGCAAGTGGG
ACGGCTTCGCCGTCGAAGACTTCCGAGAGACCGGGCGCCGTGTATCCCTGAGGCGCGGCCGCGCGGTGGCCATCTTCGAC
GAGGTCGTGCAGGCGGTCCGGCGATGGCCGGAATTCGCCGCAGAGGCCGGCGTGTCCGATTTCCACCGGGAGCAGGTGGC
GAAGTCGCTGCGGCTCGCCCTGCCGGACAAATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185469 WP_011038999.1 NZ_CP066934:c4704819-4704667 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185469 NZ_CP088247:c229394-228969 [Methylorubrum sp. B1-46]
ATGCATCTATCCCCCCTCCTGACCGACGATGCCACGCTCGGCGAGATCGGCAATCGGTTCATGCAGAGGCGCCTGCAGCG
GAACCTCACTCAGGCCGAGCTGGCCGCTCGGGCGGGCGTGTCCAAGAGGACGATCGAGCGCCTTGAGGAGGGCGGGTCGA
GCCAGTTCGCGAACGTGGTCAAGGTGATCCGCGCCCTCGACCTGTTCGACGGCCTCGACCGGCTCGTGCCCGAGGTCGGC
CCGAGCCCGATCCAGCAGGCCAAGCTCCAAGGGCGCCAGCGCAAACGCGCGTCCGGCACCGCGGCCAAGGCGGTGGCCAA
GGGGGGGGCGGCCGCCGTGGGCGCCGGTAAGCCCCGGGTCGCCTCGCGCACCAAGACGGCGGCCAAGGGCTCCGGCAAGG
CGTGGTCCTGGGGCGACGCGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References