Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4682447..4682810 Replicon chromosome
Accession NZ_CP066933
Organism Xanthomonas campestris pv. campestris strain 10108

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH304_RS20685 Protein ID WP_011270059.1
Coordinates 4682447..4682581 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH304_RS20690 Protein ID WP_011038999.1
Coordinates 4682658..4682810 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH304_RS20665 (JH304_20620) 4677712..4679364 - 1653 WP_172973909.1 M28 family metallopeptidase -
JH304_RS20670 (JH304_20625) 4679528..4680472 - 945 WP_172973853.1 MBL fold metallo-hydrolase -
JH304_RS20675 (JH304_20630) 4680556..4681845 - 1290 WP_172973854.1 tryptophan--tRNA ligase -
JH304_RS20680 (JH304_20635) 4682005..4682214 - 210 WP_011038998.1 CsbD family protein -
JH304_RS20685 (JH304_20640) 4682447..4682581 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH304_RS20690 (JH304_20645) 4682658..4682810 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH304_RS20695 (JH304_20650) 4682921..4683844 - 924 Protein_4005 arginase -
JH304_RS20700 (JH304_20655) 4684158..4684619 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JH304_RS20705 (JH304_20660) 4684702..4685061 + 360 WP_011039002.1 hypothetical protein -
JH304_RS20710 (JH304_20665) 4685164..4686081 + 918 WP_011039003.1 hypothetical protein -
JH304_RS20715 (JH304_20670) 4686078..4686620 + 543 WP_011039004.1 GTPase -
JH304_RS20720 (JH304_20675) 4686955..4687638 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185467 WP_011270059.1 NZ_CP066933:c4682581-4682447 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185467 NZ_CP088245:216879-217229 [Metabacillus sp. B2-18]
TTGATTGTTAAACGAGGCGACGTTTATTTTGCCGATCTTTCTCCAGTTGTAGGTTCAGAGCAAGGTGGCGTGCGTCCTGT
ATTAATTATTCAAAACGATATTGGGAACCGCTTTAGTCCTACAGTTATTATAGCGGCAATTACGGCCCAAATTCAAAAAG
CAAAATTGCCAACTCATGTTGAGATTGATGCTAAGCGTTACGGGTTTGAAAGGGATTCGGTTATCCTGCTTGAACAGATT
CGAACGATTGATAAACAAAGGCTTACTGATAAAATTACCCATCTAGATGATGAGATGATGGATAAAGTTGATGAAGCCTT
ACAAATAAGCTTAGGACTTATCGATTTTTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185467 WP_011038999.1 NZ_CP066933:c4682810-4682658 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185467 NZ_CP088245:216593-216874 [Metabacillus sp. B2-18]
GTGTCTGAATCCAGCGCAACAACAGAAATTTTAATTCAGTTACCTCAAGCATTAGTATCAGAATTGGATGTATTGGTAAA
ACAAGAGAACGGGAACAGAAACGAGCTTATTTATCAAGCGACAAAAATGTATATTCGTGAGCGTAAAAAGCGCCAAATTC
GTGAGTCTATGAGACGTGGTTACATGGAAATGGCAAAAATCAATTTGAATATTGCATCTGAAGCATTTTTGGCAGAATCT
GAGGCTGACCATACCGTTGAACGCTTAGTCAGCGGGGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References