185464

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4773884..4774247 Replicon chromosome
Accession NZ_CP066931
Organism Xanthomonas campestris pv. raphani strain 609

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH270_RS20875 Protein ID WP_011270059.1
Coordinates 4773884..4774018 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH270_RS20880 Protein ID WP_011038999.1
Coordinates 4774095..4774247 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH270_RS20855 (JH270_20835) 4769149..4770801 - 1653 WP_274342162.1 M28 family metallopeptidase -
JH270_RS20860 (JH270_20840) 4770966..4771910 - 945 WP_274341197.1 MBL fold metallo-hydrolase -
JH270_RS20865 (JH270_20845) 4771994..4773283 - 1290 WP_043922084.1 tryptophan--tRNA ligase -
JH270_RS20870 (JH270_20850) 4773444..4773653 - 210 WP_011038998.1 CsbD family protein -
JH270_RS20875 (JH270_20855) 4773884..4774018 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH270_RS20880 (JH270_20860) 4774095..4774247 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH270_RS20885 (JH270_20865) 4774358..4775281 - 924 WP_011039000.1 arginase -
JH270_RS20890 (JH270_20870) 4775595..4776056 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH270_RS20895 (JH270_20875) 4776139..4776498 + 360 WP_011039002.1 hypothetical protein -
JH270_RS20900 (JH270_20880) 4776601..4777518 + 918 WP_014506231.1 hypothetical protein -
JH270_RS20905 (JH270_20885) 4777515..4778057 + 543 WP_076035808.1 GTPase -
JH270_RS20910 (JH270_20890) 4778390..4779073 + 684 WP_274341198.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185464 WP_011270059.1 NZ_CP066931:c4774018-4773884 [Xanthomonas campestris pv. raphani]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185464 NZ_CP088243:c1258100-1257822 [Stenotrophomonas maltophilia]
ATGATCCGTTCATTCCGCTGCAAGCAGACCCGCGCCCTGTTTGAAGGAGCCTGCCCTCGCGCTTGGCGCCCGATACGACG
CGCGGCTGAACGTAAACTCCAGCTGCTCGATTCGGCACAGACGCTGGCCTTCCTGCGCAGCCCGCCCGGGAATCGTCTTG
AGGCGCTGTCAGGTGATCGGAGAGGACAATACAGCCTCCGTATCAATGATCAGTGGCGGCTCTGTTTCACCTGGACCGAC
AGCGGCGCCGATGCCGTGGAAATTGTTGACTATCACTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185464 WP_011038999.1 NZ_CP066931:c4774247-4774095 [Xanthomonas campestris pv. raphani]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185464 NZ_CP088243:c1257811-1257512 [Stenotrophomonas maltophilia]
ATGAAGCGTCCCCACAACGGCATGCGCGCCATCCATCCTGGCGAGATCCTGCGCGAAGAGTTTCTGCTGCCCCTGTCGCT
GAGCGTGAATGCGCTGGCGAAGGCGCTGGATGTTCCCGCAACGCGGCTGCACGCCATCGTCCACGGTCAGCGCAGCATCT
CGGCGGACACGGCAGCGCGGTTGGCACGGCATTTCGGCGGGGATGCCGCTTCCTGGCTTGCGATGCAGGCGGCCTACGAT
CTCAAGACATTGCCAACACGCAGCGAGATCGAACGCCGCGTACAGCCTCGGGCGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References