Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/PIN-MazE |
Location | 2609527..2610160 | Replicon | chromosome |
Accession | NZ_CP066931 | ||
Organism | Xanthomonas campestris pv. raphani strain 609 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | JH270_RS11075 | Protein ID | WP_274340510.1 |
Coordinates | 2609747..2610160 (+) | Length | 138 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | JH270_RS11070 | Protein ID | WP_274340509.1 |
Coordinates | 2609527..2609760 (+) | Length | 78 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JH270_RS11060 (JH270_11075) | 2606662..2608197 | + | 1536 | WP_274340508.1 | hypothetical protein | - |
JH270_RS11065 (JH270_11080) | 2608604..2609227 | + | 624 | WP_228316184.1 | hypothetical protein | - |
JH270_RS11070 (JH270_11085) | 2609527..2609760 | + | 234 | WP_274340509.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
JH270_RS11075 (JH270_11090) | 2609747..2610160 | + | 414 | WP_274340510.1 | PIN domain-containing protein | Toxin |
JH270_RS11080 (JH270_11095) | 2610184..2610552 | + | 369 | WP_274340511.1 | DUF3742 family protein | - |
JH270_RS11085 (JH270_11100) | 2610557..2612074 | - | 1518 | WP_274340512.1 | conjugal transfer protein TraG N-terminal domain-containing protein | - |
JH270_RS11090 (JH270_11105) | 2612462..2612860 | - | 399 | WP_274340513.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 2567596..2616999 | 49403 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 15399.88 Da Isoelectric Point: 6.4740
>T185463 WP_274340510.1 NZ_CP066931:2609747-2610160 [Xanthomonas campestris pv. raphani]
MIGGKAKIFLDSNVVLYLLSEDSAKADDAEKLVQRRPIISVQVLNEVTHVCVRKLKMGWGEVGQFLALVREFCKVVPLTV
DVHDRARQLAERHQLSFYDACIIAAAAIEGCQTLYTEDMRHGLIIEESLSIRNPFNT
MIGGKAKIFLDSNVVLYLLSEDSAKADDAEKLVQRRPIISVQVLNEVTHVCVRKLKMGWGEVGQFLALVREFCKVVPLTV
DVHDRARQLAERHQLSFYDACIIAAAAIEGCQTLYTEDMRHGLIIEESLSIRNPFNT
Download Length: 414 bp
>T185463 NZ_CP088242:c113431-113153 [Stenotrophomonas maltophilia]
ATGATCCGTTCATTCCGCTGCAAGCAGACCCGCGCCCTGTTTGAAGGAGCCTGCCCTCGCGCTTGGCGCCCGATACGACG
CGCGGCTGAACGTAAACTCCAGCTGCTCGATTCGGCACAGACGCTGGCCTTCCTGCGCAGCCCGCCCGGGAATCGTCTTG
AGGCGCTGTCAGGTGATCGGAGAGGACAATACAGCCTCCGTATCAATGATCAGTGGCGGCTCTGTTTCACCTGGACCGAC
AGCGGCGCCGATGCCGTGGAAATTGTTGACTATCACTGA
ATGATCCGTTCATTCCGCTGCAAGCAGACCCGCGCCCTGTTTGAAGGAGCCTGCCCTCGCGCTTGGCGCCCGATACGACG
CGCGGCTGAACGTAAACTCCAGCTGCTCGATTCGGCACAGACGCTGGCCTTCCTGCGCAGCCCGCCCGGGAATCGTCTTG
AGGCGCTGTCAGGTGATCGGAGAGGACAATACAGCCTCCGTATCAATGATCAGTGGCGGCTCTGTTTCACCTGGACCGAC
AGCGGCGCCGATGCCGTGGAAATTGTTGACTATCACTGA
Antitoxin
Download Length: 78 a.a. Molecular weight: 8719.98 Da Isoelectric Point: 6.3548
>AT185463 WP_274340509.1 NZ_CP066931:2609527-2609760 [Xanthomonas campestris pv. raphani]
MQVAKWGNSLAVRLPASLVEALELREGDDIEIVVDEPRLFAVRKKPGSDALLERLRAFRGKLPADFRFNREEANDRG
MQVAKWGNSLAVRLPASLVEALELREGDDIEIVVDEPRLFAVRKKPGSDALLERLRAFRGKLPADFRFNREEANDRG
Download Length: 234 bp
>AT185463 NZ_CP088242:c113142-112843 [Stenotrophomonas maltophilia]
ATGAAGCGTCCCCACAACGGCATGCGCGCCATCCATCCTGGCGAGATCCTGCGCGAAGAGTTTCTGCTGCCCCTGTCGCT
GAGCGTGAATGCGCTGGCGAAGGCGCTGGATGTTCCCGCAACGCGGCTGCACGCCATCGTCCACGGTCAGCGCAGCATCT
CGGCGGACACGGCAGCGCGGTTGGCACGGCATTTCGGCGGGGATGCCGCTTCCTGGCTTGCGATGCAGGCGGCCTACGAT
CTCAAGACATTGCCAACACGCAGCGAGATCGAACGCCGCGTACAGCCTCGGGCGGCATGA
ATGAAGCGTCCCCACAACGGCATGCGCGCCATCCATCCTGGCGAGATCCTGCGCGAAGAGTTTCTGCTGCCCCTGTCGCT
GAGCGTGAATGCGCTGGCGAAGGCGCTGGATGTTCCCGCAACGCGGCTGCACGCCATCGTCCACGGTCAGCGCAGCATCT
CGGCGGACACGGCAGCGCGGTTGGCACGGCATTTCGGCGGGGATGCCGCTTCCTGGCTTGCGATGCAGGCGGCCTACGAT
CTCAAGACATTGCCAACACGCAGCGAGATCGAACGCCGCGTACAGCCTCGGGCGGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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