185461

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 335019..335385 Replicon chromosome
Accession NZ_CP066930
Organism Xanthomonas campestris pv. raphani strain 719

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH264_RS01385 Protein ID WP_011270059.1
Coordinates 335251..335385 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH264_RS01380 Protein ID WP_011038999.1
Coordinates 335019..335171 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH264_RS01350 (JH264_01350) 330191..330874 - 684 WP_076057144.1 dTMP kinase -
JH264_RS01355 (JH264_01355) 331209..331751 - 543 WP_042595653.1 GTPase -
JH264_RS01360 (JH264_01360) 331748..332665 - 918 WP_076057143.1 hypothetical protein -
JH264_RS01365 (JH264_01365) 332768..333127 - 360 WP_011039002.1 hypothetical protein -
JH264_RS01370 (JH264_01370) 333210..333671 - 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH264_RS01375 (JH264_01375) 333985..334908 + 924 WP_076057526.1 arginase -
JH264_RS01380 (JH264_01380) 335019..335171 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH264_RS01385 (JH264_01385) 335251..335385 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH264_RS01390 (JH264_01390) 335618..335827 + 210 WP_011038998.1 CsbD family protein -
JH264_RS01395 (JH264_01395) 335987..337276 + 1290 WP_043922084.1 tryptophan--tRNA ligase -
JH264_RS01400 (JH264_01400) 337360..338304 + 945 WP_176994121.1 MBL fold metallo-hydrolase -
JH264_RS01405 (JH264_01405) 338469..340121 + 1653 WP_162275546.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185461 WP_011270059.1 NZ_CP066930:335251-335385 [Xanthomonas campestris pv. raphani]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185461 NZ_CP088241:c1809536-1809231 [Stenotrophomonas maltophilia]
ATGAAGATCCAGCGTACCCGTCAGTTCGCGACATGGATTGACGCTCTCAAGGACGTAACCGCACGCGCTCGCATCCTGGC
CCGTATCGGTCGGCTCGCTGAAGGCCATCCTGGTGATCACCGCTATCTGGCGGATGGCGTTTCTGAATTGCGTATCGATG
CAGGACCCGGTTACCGCGTGTACTACACCCAGCGGGGCAGGCAGTTGGTGATTCTTCTGGTCGGAGGCGACAAGGGTTCG
CAACAGCGCGATATAGAGAAGGCCAAGGAGATTGCGCGTGCCCTGCGAGCATCGAACTGGTTGTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185461 WP_011038999.1 NZ_CP066930:335019-335171 [Xanthomonas campestris pv. raphani]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185461 NZ_CP088241:c1809190-1808888 [Stenotrophomonas maltophilia]
ATGGCTATCAAGAAGAAAGTTGAACTCGAAGCATTTGATGTGGCCGAACACCTTCATACACCGAAGGAAATGGCGGCCTA
TCTCGATGCATGCATCGAAGAAAGCGACGGCGATTCGGCATTCATCGCCAAGGCGCTGGGCGATATCGCGCGTGCCCAAG
GGATGAGCAAGGTCGCACGTGCGGCGGGCCTGTCGCGGGAGAGTCTGTATCGTGCCCTGTCTGGCGAGCGCAGCCCTGAT
TTCTCGACCATCCTGAAGGTGACTCGTGCCCTGGGTGTGCGCCTGCATGCCAGCGCTGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References