185460

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4715474..4715840 Replicon chromosome
Accession NZ_CP066929
Organism Xanthomonas campestris pv. campestris strain CFBP12825

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH272_RS20875 Protein ID WP_011270059.1
Coordinates 4715474..4715608 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH272_RS20880 Protein ID WP_011038999.1
Coordinates 4715688..4715840 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH272_RS20855 (JH272_20750) 4710737..4712389 - 1653 WP_227972034.1 M28 family metallopeptidase -
JH272_RS20860 (JH272_20755) 4712554..4713498 - 945 WP_187305905.1 MBL fold metallo-hydrolase -
JH272_RS20865 (JH272_20760) 4713582..4714871 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH272_RS20870 (JH272_20765) 4715031..4715240 - 210 WP_011038998.1 CsbD family protein -
JH272_RS20875 (JH272_20770) 4715474..4715608 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH272_RS20880 (JH272_20775) 4715688..4715840 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH272_RS20885 (JH272_20780) 4715951..4716874 - 924 WP_040942405.1 arginase -
JH272_RS20890 (JH272_20785) 4717188..4717649 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH272_RS20895 (JH272_20790) 4717732..4718091 + 360 WP_011039002.1 hypothetical protein -
JH272_RS20900 (JH272_20795) 4718194..4719111 + 918 WP_267314525.1 hypothetical protein -
JH272_RS20905 (JH272_20800) 4719108..4719650 + 543 WP_012439507.1 GTPase -
JH272_RS20910 (JH272_20805) 4719984..4720667 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185460 WP_011270059.1 NZ_CP066929:c4715608-4715474 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185460 NZ_CP088241:c1809190-1808888 [Stenotrophomonas maltophilia]
ATGGCTATCAAGAAGAAAGTTGAACTCGAAGCATTTGATGTGGCCGAACACCTTCATACACCGAAGGAAATGGCGGCCTA
TCTCGATGCATGCATCGAAGAAAGCGACGGCGATTCGGCATTCATCGCCAAGGCGCTGGGCGATATCGCGCGTGCCCAAG
GGATGAGCAAGGTCGCACGTGCGGCGGGCCTGTCGCGGGAGAGTCTGTATCGTGCCCTGTCTGGCGAGCGCAGCCCTGAT
TTCTCGACCATCCTGAAGGTGACTCGTGCCCTGGGTGTGCGCCTGCATGCCAGCGCTGCATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185460 WP_011038999.1 NZ_CP066929:c4715840-4715688 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185460 NZ_CP088241:c1809536-1809231 [Stenotrophomonas maltophilia]
ATGAAGATCCAGCGTACCCGTCAGTTCGCGACATGGATTGACGCTCTCAAGGACGTAACCGCACGCGCTCGCATCCTGGC
CCGTATCGGTCGGCTCGCTGAAGGCCATCCTGGTGATCACCGCTATCTGGCGGATGGCGTTTCTGAATTGCGTATCGATG
CAGGACCCGGTTACCGCGTGTACTACACCCAGCGGGGCAGGCAGTTGGTGATTCTTCTGGTCGGAGGCGACAAGGGTTCG
CAACAGCGCGATATAGAGAAGGCCAAGGAGATTGCGCGTGCCCTGCGAGCATCGAACTGGTTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References