Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 339131..339494 Replicon chromosome
Accession NZ_CP066928
Organism Xanthomonas campestris pv. incanae strain CFBP1371

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH299_RS01415 Protein ID WP_011270059.1
Coordinates 339360..339494 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH299_RS01410 Protein ID WP_011038999.1
Coordinates 339131..339283 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH299_RS01380 (JH299_01385) 334309..334986 - 678 WP_076035807.1 dTMP kinase -
JH299_RS01385 (JH299_01390) 335321..335863 - 543 WP_076035808.1 GTPase -
JH299_RS01390 (JH299_01395) 335860..336777 - 918 WP_076035809.1 hypothetical protein -
JH299_RS01395 (JH299_01400) 336880..337239 - 360 WP_011039002.1 hypothetical protein -
JH299_RS01400 (JH299_01405) 337322..337783 - 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH299_RS01405 (JH299_01410) 338097..339020 + 924 Protein_269 arginase -
JH299_RS01410 (JH299_01415) 339131..339283 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH299_RS01415 (JH299_01420) 339360..339494 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH299_RS01420 (JH299_01425) 339726..339935 + 210 WP_011038998.1 CsbD family protein -
JH299_RS01425 (JH299_01430) 340095..341384 + 1290 WP_043922084.1 tryptophan--tRNA ligase -
JH299_RS01430 (JH299_01435) 341468..342412 + 945 WP_175611475.1 MBL fold metallo-hydrolase -
JH299_RS01435 (JH299_01440) 342577..344229 + 1653 WP_175611788.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185457 WP_011270059.1 NZ_CP066928:339360-339494 [Xanthomonas campestris pv. incanae]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185457 NZ_CP088229:c4035149-4034808 [Enterobacter kobei]
ATGAAAACTTTACCTGCAACAACTCAGCGGGCGGTGAAGCCCTGCCTGTCACCCGTGGCTGTCTGGCAAATGCTACTGAC
ACGCCTGCTGGAACAGCACTATGGTCTCACCCTCAACGACACACCGTTCAGTGAGGAACGTGTTATACAGGAACATATCG
ATGCCGGGATCTCGCTGGCTGATGCCGTGAATTTTCTGGTGGAAAAATACGAACTGGTGCGTATCGACAGGAAGGGATTT
AACTGGCAGGAACAATCCCCTTATCTCCGGGCTGTAGACATTCTGCGAGCGCGGCAGGCAACTGGCTTGTTGCGGCAAAG
CCGTAAAAATTCGGTACGGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185457 WP_011038999.1 NZ_CP066928:339131-339283 [Xanthomonas campestris pv. incanae]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185457 NZ_CP088229:c4035487-4035170 [Enterobacter kobei]
ATGACTCACATCACATGGGGCCTGCAGCGGAATATCACGCCGCGCCTGGGAGCCCGTCTGGTGCAGGAAGGGAACCGGAT
GCATTATCTGGCTGACCGGGCCAGCATCACCGGCAAGTTCAGTGACACCGAATGCCGGAAGCTGGATGAAACATTCCCGC
ACTTTATCCGCCAGATGGAATCGATGCTGACCACTGGTGAAATGAATCCCCGCAATGCCCACTGTGTCACCCTGTTCCAC
AACGGTTTCACATGTGAAGCCGACACCCTTGGCAGTTGCGGTTACGTGTACATCGCCATTTATCCCACCCAGCGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References