Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | EcnAB/- |
Location | 4521884..4522247 | Replicon | chromosome |
Accession | NZ_CP066926 | ||
Organism | Xanthomonas campestris pv. incanae strain CFBP6690 |
Toxin (Protein)
Gene name | EcnB | Uniprot ID | G0CKD4 |
Locus tag | JH261_RS19430 | Protein ID | WP_011270059.1 |
Coordinates | 4521884..4522018 (-) | Length | 45 a.a. |
Antitoxin (Protein)
Gene name | EcnA | Uniprot ID | Q8P3Z2 |
Locus tag | JH261_RS19435 | Protein ID | WP_011038999.1 |
Coordinates | 4522095..4522247 (-) | Length | 51 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JH261_RS19410 (JH261_19410) | 4517148..4518800 | - | 1653 | WP_274318722.1 | M28 family metallopeptidase | - |
JH261_RS19415 (JH261_19415) | 4518965..4519909 | - | 945 | WP_274317732.1 | MBL fold metallo-hydrolase | - |
JH261_RS19420 (JH261_19420) | 4519993..4521282 | - | 1290 | WP_161962176.1 | tryptophan--tRNA ligase | - |
JH261_RS19425 (JH261_19425) | 4521443..4521652 | - | 210 | WP_011038998.1 | CsbD family protein | - |
JH261_RS19430 (JH261_19430) | 4521884..4522018 | - | 135 | WP_011270059.1 | entericidin A/B family lipoprotein | Toxin |
JH261_RS19435 (JH261_19435) | 4522095..4522247 | - | 153 | WP_011038999.1 | entericidin A/B family lipoprotein | Antitoxin |
JH261_RS19440 (JH261_19440) | 4522358..4523281 | - | 924 | WP_274317733.1 | arginase | - |
JH261_RS19445 (JH261_19445) | 4523595..4524056 | + | 462 | WP_042595651.1 | roadblock/LC7 domain-containing protein | - |
JH261_RS19450 (JH261_19450) | 4524139..4524498 | + | 360 | WP_011039002.1 | hypothetical protein | - |
JH261_RS19455 (JH261_19455) | 4524591..4525508 | + | 918 | WP_228944310.1 | hypothetical protein | - |
JH261_RS19460 (JH261_19460) | 4525505..4526047 | + | 543 | WP_076035808.1 | GTPase | - |
JH261_RS19465 (JH261_19465) | 4526382..4527065 | + | 684 | WP_050911792.1 | dTMP kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4431.27 Da Isoelectric Point: 9.3487
>T185456 WP_011270059.1 NZ_CP066926:c4522018-4521884 [Xanthomonas campestris pv. incanae]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
Download Length: 135 bp
>T185456 NZ_CP088229:c3819823-3819413 [Enterobacter kobei]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCGTTAATGCTCCACGGCCTGGTTGCGGC
CATCGTGTTACTCATGCCATGGCCCCTGAGCTATACACCGCTGTGGCTGCTATTACTTTCGTTTGTCGTTTTTGACAGCG
TACGCAGCCAGCGTCGCATTAATGCTCGTCAGGGTGAGATCAAGTTACTGATGGATTCCCGCCTGCGCTGGCAGGGAAAA
GAGTGGGATATTCTGGGTATGCCATGGATGCTCAACTCCGGCATGATGTTACGGTTACGCAATGTGGACGGCGGGCGTTG
CCAGCACCTGTGGCTGGCGGCTGACAGTATGGATGCTTCAGAATGGCGAGATCTGCGCCGGATGTTGTTGCAACAGCCGA
CGCAGGAGTAA
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCGTTAATGCTCCACGGCCTGGTTGCGGC
CATCGTGTTACTCATGCCATGGCCCCTGAGCTATACACCGCTGTGGCTGCTATTACTTTCGTTTGTCGTTTTTGACAGCG
TACGCAGCCAGCGTCGCATTAATGCTCGTCAGGGTGAGATCAAGTTACTGATGGATTCCCGCCTGCGCTGGCAGGGAAAA
GAGTGGGATATTCTGGGTATGCCATGGATGCTCAACTCCGGCATGATGTTACGGTTACGCAATGTGGACGGCGGGCGTTG
CCAGCACCTGTGGCTGGCGGCTGACAGTATGGATGCTTCAGAATGGCGAGATCTGCGCCGGATGTTGTTGCAACAGCCGA
CGCAGGAGTAA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5173.15 Da Isoelectric Point: 8.2782
>AT185456 WP_011038999.1 NZ_CP066926:c4522247-4522095 [Xanthomonas campestris pv. incanae]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC
Download Length: 153 bp
>AT185456 NZ_CP088229:c3820070-3819804 [Enterobacter kobei]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCATGCCGTCGCGGCATGCGTGAACTTGATATTTCCATCATGCCTTT
CTTCGAATATGAGTATGACAGCTTAAGCGATGATGATAAGCGGCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCAGATT
TATTCAACTGGCTGATGAACCACGGCAAACCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCATGCCGTCGCGGCATGCGTGAACTTGATATTTCCATCATGCCTTT
CTTCGAATATGAGTATGACAGCTTAAGCGATGATGATAAGCGGCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCAGATT
TATTCAACTGGCTGATGAACCACGGCAAACCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H2XDQ0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q8P3Z2 |