Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1345287..1346065 Replicon chromosome
Accession NZ_CP066926
Organism Xanthomonas campestris pv. incanae strain CFBP6690

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag JH261_RS05535 Protein ID WP_274318279.1
Coordinates 1345287..1345778 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag JH261_RS05540 Protein ID WP_274318280.1
Coordinates 1345775..1346065 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH261_RS05520 (JH261_05505) 1341615..1342490 + 876 WP_274318278.1 30S ribosomal protein S6--L-glutamate ligase -
JH261_RS05525 (JH261_05510) 1343140..1343817 + 678 WP_003490678.1 response regulator transcription factor -
JH261_RS05530 (JH261_05515) 1343810..1345144 + 1335 WP_019237347.1 HAMP domain-containing sensor histidine kinase -
JH261_RS05535 (JH261_05520) 1345287..1345778 - 492 WP_274318279.1 GNAT family N-acetyltransferase Toxin
JH261_RS05540 (JH261_05525) 1345775..1346065 - 291 WP_274318280.1 DUF1778 domain-containing protein Antitoxin
JH261_RS05545 (JH261_05530) 1346141..1346542 - 402 WP_274318281.1 SymE family type I addiction module toxin -
JH261_RS05550 (JH261_05535) 1347074..1347697 - 624 WP_228424129.1 dephospho-CoA kinase -
JH261_RS05555 (JH261_05540) 1347711..1348574 - 864 WP_011038216.1 A24 family peptidase -
JH261_RS05560 (JH261_05545) 1348581..1349843 - 1263 WP_274318282.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17610.29 Da        Isoelectric Point: 8.1176

>T185455 WP_274318279.1 NZ_CP066926:c1345778-1345287 [Xanthomonas campestris pv. incanae]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGKGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Download         Length: 492 bp

>T185455 NZ_CP088229:c2823686-2823583 [Enterobacter kobei]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10648.24 Da        Isoelectric Point: 10.6886

>AT185455 WP_274318280.1 NZ_CP066926:c1346065-1345775 [Xanthomonas campestris pv. incanae]
MSTPDTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLIAASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWKKA

Download         Length: 291 bp

>AT185455 NZ_CP088229:2823576-2823721 [Enterobacter kobei]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References