185453

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 355411..355774 Replicon chromosome
Accession NZ_CP066925
Organism Xanthomonas campestris strain CFBP5824

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH314_RS01475 Protein ID WP_011270059.1
Coordinates 355640..355774 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH314_RS01470 Protein ID WP_011038999.1
Coordinates 355411..355563 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH314_RS01440 (JH314_01450) 350583..351266 - 684 WP_274339650.1 dTMP kinase -
JH314_RS01445 (JH314_01455) 351601..352143 - 543 WP_076035808.1 GTPase -
JH314_RS01450 (JH314_01460) 352140..353057 - 918 WP_014506231.1 hypothetical protein -
JH314_RS01455 (JH314_01465) 353160..353519 - 360 WP_011039002.1 hypothetical protein -
JH314_RS01460 (JH314_01470) 353602..354063 - 462 WP_274339651.1 roadblock/LC7 domain-containing protein -
JH314_RS01465 (JH314_01475) 354377..355300 + 924 WP_274339652.1 arginase -
JH314_RS01470 (JH314_01480) 355411..355563 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH314_RS01475 (JH314_01485) 355640..355774 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH314_RS01480 (JH314_01490) 356006..356215 + 210 WP_011038998.1 CsbD family protein -
JH314_RS01485 (JH314_01495) 356375..357664 + 1290 WP_057673596.1 tryptophan--tRNA ligase -
JH314_RS01490 (JH314_01500) 357748..358692 + 945 WP_274339654.1 MBL fold metallo-hydrolase -
JH314_RS01495 (JH314_01505) 358857..360509 + 1653 WP_161962238.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185453 WP_011270059.1 NZ_CP066925:355640-355774 [Xanthomonas campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185453 NZ_CP088229:c1150600-1150238 [Enterobacter kobei]
ATGTGGAATGTCGAGACAACGGACAGATTTGATCAATGGTACTTCGAACAAACAACAGCATTAAAAGAAGATGTGCTAGC
GATGATGCATATTCTTGCTGAGTTTGGCCCAACGCTTGGGCGGCCATACGTAGATACCGTGAAGGCTTCAGCCTATGCGA
ACATGAAGGAATTACGGATTCAACATGCGGGAAATCCCATCAGAGCTTTTTTTGCTTTTGATCCTGACCGTAAGGCAATT
GTGCTCTGTGCTGGAGACAAAACCGGTTGCAATCAAAAACGGTTTTATAACGAAATGATTACGCTGGCTGACGTTGAGTA
CAGCAGACATCTGGCGGATAAGGAGGCCATATGGCAACGCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185453 WP_011038999.1 NZ_CP066925:355411-355563 [Xanthomonas campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185453 NZ_CP088229:c1150250-1149951 [Enterobacter kobei]
ATGGCAACGCTAAAAGAACTCATGGCACAACAGAGCGCGGAAAGTCAGGAGCGTATTGCGGCTAAAGTTGATGTAATACG
AAGAATTGTTGCCCTGAACCAACTGCGGGAAGAGCTCAATATTTCGCAGACAGAACTGGCCGCGGCAATGGGGGTAAAAC
AACCCACTGTGGCAAAAATCGAACAGCCGGGAAACGATCCCCGGCTTTCAACACTCAAACGCTATGTCAGTGCGCTCGGC
GGTGAAATGAGCATTGATGTGACGTTACCGAATGGGAAACGAATAGCGTTTCAGATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References