Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 4991220..4991626 Replicon chromosome
Accession NZ_CP066923
Organism Xanthomonas campestris pv. incanae strain CFBP1606

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH295_RS21715 Protein ID WP_267129426.1
Coordinates 4991471..4991626 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH295_RS21710 Protein ID WP_070694028.1
Coordinates 4991220..4991474 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH295_RS21685 (JH295_21640) 4986990..4987538 + 549 WP_070694016.1 RNA 2'-phosphotransferase -
JH295_RS21690 (JH295_21645) 4987704..4988969 + 1266 WP_070694019.1 phospholipase D-like domain-containing protein -
JH295_RS21695 (JH295_21650) 4989001..4989516 - 516 WP_070694020.1 hypothetical protein -
JH295_RS21700 (JH295_21655) 4989773..4989979 + 207 WP_070694021.1 hypothetical protein -
JH295_RS21705 (JH295_21660) 4989966..4991081 + 1116 WP_070694026.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH295_RS21710 (JH295_21665) 4991220..4991474 + 255 WP_070694028.1 Arc family DNA-binding protein Antitoxin
JH295_RS21715 (JH295_21670) 4991471..4991626 + 156 WP_267129426.1 hypothetical protein Toxin
JH295_RS21720 (JH295_21675) 4991681..4992652 - 972 WP_081340836.1 DUF2971 domain-containing protein -
JH295_RS21725 (JH295_21680) 4992811..4994431 + 1621 Protein_4200 alpha/beta hydrolase-fold protein -
JH295_RS21730 (JH295_21685) 4994995..4995396 - 402 WP_016945062.1 DUF2384 domain-containing protein -
JH295_RS21735 (JH295_21690) 4995712..4996167 + 456 WP_070694033.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5681.63 Da        Isoelectric Point: 4.3220

>T185452 WP_267129426.1 NZ_CP066923:4991471-4991626 [Xanthomonas campestris pv. incanae]
VTLLDTNVIFGPNLHVVAWIDVQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185452 NZ_CP088229:c1059824-1059606 [Enterobacter kobei]
ATGTCTGAAAAACCACTCACAAAGGTCGATTATTTGATGCGCTTACGTCGTTGTCAGTCAATTGACACCCTCGAACGCGT
CATTGAAAAGAATAAATACGAGCTTTCTGATAATGAACTGGCGGTATTTTATTCAGCTGCTGACCATCGCCTCGCTGAGC
TAACGATGAATAAGTTATATGACAAAATCCCCACATCCGTGTGGAAATTTGTTCGTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9028.44 Da        Isoelectric Point: 10.3861

>AT185452 WP_070694028.1 NZ_CP066923:4991220-4991474 [Xanthomonas campestris pv. incanae]
MPSFTVRNIPEDVHRAIWARAAQHGRSTEAEIRAILESAAKPADQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185452 NZ_CP088229:c1060226-1059852 [Enterobacter kobei]
ATGGACGAGTACTCGCCAAAACGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAATCTTGATGAAAGTAACCATGGCTGGGTAAACGATCCAACGTCTGCCATCAATTTACAGTTGAACGAGCTTATCGAGC
ATATCGCTACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGCTCATTGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGTAGTTACGGCATTAACGCTCAGGATTTGCAAAAATGGCGCAAATCGGGAAACCGACT
ATTCCGCTGTTTCGTCAACGTGAGCAGAGCTAACCCCGTTAGCCTTTCCTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References