Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 394779..395145 Replicon chromosome
Accession NZ_CP066922
Organism Xanthomonas campestris strain 5053

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH280_RS01580 Protein ID WP_011270059.1
Coordinates 395011..395145 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH280_RS01575 Protein ID WP_011038999.1
Coordinates 394779..394931 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH280_RS01545 (JH280_01555) 389957..390634 - 678 WP_274348092.1 dTMP kinase -
JH280_RS01550 (JH280_01560) 390969..391511 - 543 WP_042595653.1 GTPase -
JH280_RS01555 (JH280_01565) 391508..392425 - 918 WP_274348093.1 hypothetical protein -
JH280_RS01560 (JH280_01570) 392528..392887 - 360 WP_011039002.1 hypothetical protein -
JH280_RS01565 (JH280_01575) 392970..393431 - 462 WP_042595651.1 roadblock/LC7 domain-containing protein -
JH280_RS01570 (JH280_01580) 393745..394668 + 924 WP_274348094.1 arginase -
JH280_RS01575 (JH280_01585) 394779..394931 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH280_RS01580 (JH280_01590) 395011..395145 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH280_RS01585 (JH280_01595) 395378..395587 + 210 WP_274348095.1 CsbD family protein -
JH280_RS01590 (JH280_01600) 395748..397037 + 1290 WP_274348096.1 tryptophan--tRNA ligase -
JH280_RS01595 (JH280_01605) 397121..398065 + 945 WP_274348097.1 MBL fold metallo-hydrolase -
JH280_RS01600 (JH280_01610) 398230..399882 + 1653 WP_161962238.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185449 WP_011270059.1 NZ_CP066922:395011-395145 [Xanthomonas campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185449 NZ_CP088224:317-592 [Enterobacter hormaechei]
ATGACCACAAGGATGATTGAATACTCAGGCCAGTTCCAGAAAGATGTGAAGAAGGCTCAGAAGCGTCATAAAGACATGAG
CAAGCTTAAAGCCCTTATGACGCTGTTAATCAATGATGCCTTGCCATTGCCTCAAGTCTACAAAGATCACCCTCTACAGG
GGAACTACAAAGGCTATAGGGATGCTCACATAGAACCGGACTGGCTACTCATCTACAAGATAACTGATGAAGTCCTACGC
TTTGAGCGAACCGGAACACATTCAGACCTGTTTTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185449 WP_011038999.1 NZ_CP066922:394779-394931 [Xanthomonas campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185449 NZ_CP088224:53-313 [Enterobacter hormaechei]
ATGGCCGCAAATGCATTTGTTCGTGCTCGTATAGATGAAACACTGAAAAATGAAGCTGCAGTAGTGCTTGCCGGAATGGG
CTTAACCGTTTCCGATCTGGTTCGTATCACTCTGACTAAGGTAGCTAAAGAAAAGGCTCTGCCGTTCGATATGCGTGTTC
CTAACGAGCTTACTGCTAATACCATCGCTAACAGTGAGAAAGGCGTAGACGTTCATACAGCTAAAGATGCTGATGATCTG
TTTAATCAGCTTGGTATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References