185448

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4608144..4608510 Replicon chromosome
Accession NZ_CP066921
Organism Xanthomonas campestris pv. raphani strain 5055

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH283_RS19885 Protein ID WP_011270059.1
Coordinates 4608144..4608278 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH283_RS19890 Protein ID WP_011038999.1
Coordinates 4608358..4608510 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH283_RS19865 (JH283_19790) 4603411..4605063 - 1653 WP_274299770.1 M28 family metallopeptidase -
JH283_RS19870 (JH283_19795) 4605228..4606172 - 945 WP_274298824.1 MBL fold metallo-hydrolase -
JH283_RS19875 (JH283_19800) 4606255..4607544 - 1290 WP_274298825.1 tryptophan--tRNA ligase -
JH283_RS19880 (JH283_19805) 4607704..4607913 - 210 WP_011038998.1 CsbD family protein -
JH283_RS19885 (JH283_19810) 4608144..4608278 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH283_RS19890 (JH283_19815) 4608358..4608510 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH283_RS19895 (JH283_19820) 4608621..4609544 - 924 WP_274298826.1 arginase -
JH283_RS19900 (JH283_19825) 4609858..4610319 + 462 WP_228422658.1 roadblock/LC7 domain-containing protein -
JH283_RS19905 (JH283_19830) 4610402..4610761 + 360 WP_011039002.1 hypothetical protein -
JH283_RS19910 (JH283_19835) 4610864..4611781 + 918 WP_014506231.1 hypothetical protein -
JH283_RS19915 (JH283_19840) 4611778..4612320 + 543 WP_076035808.1 GTPase -
JH283_RS19920 (JH283_19845) 4612655..4613338 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185448 WP_011270059.1 NZ_CP066921:c4608278-4608144 [Xanthomonas campestris pv. raphani]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185448 NZ_CP088223:c219940-219653 [Enterobacter hormaechei]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185448 WP_011038999.1 NZ_CP066921:c4608510-4608358 [Xanthomonas campestris pv. raphani]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185448 NZ_CP088223:c220179-219940 [Enterobacter hormaechei]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References