Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3476373..3476518 Replicon chromosome
Accession NZ_CP066915
Organism Klebsiella pneumoniae strain XHKPN391

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3476380..3476482 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3476373..3476518 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG797_RS17175 3471905..3473338 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
JG797_RS17180 3473454..3473693 + 240 WP_002911393.1 YebV family protein -
JG797_RS17185 3473791..3473982 + 192 WP_002911395.1 YebW family protein -
JG797_RS17190 3473979..3474632 - 654 WP_206640633.1 protein-serine/threonine phosphatase -
JG797_RS17195 3474789..3475757 + 969 WP_004151446.1 VirK/YbjX family protein -
JG797_RS17200 3475862..3476005 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3476373..3476518 + 146 - - Antitoxin
- 3476380..3476482 - 103 - - Toxin
JG797_RS17205 3476641..3476979 - 339 WP_002911404.1 YebY family protein -
JG797_RS17210 3476996..3477865 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
JG797_RS17215 3477869..3478243 - 375 WP_004151448.1 CopC domain-containing protein YobA -
JG797_RS17220 3478356..3478586 + 231 WP_002911406.1 DNA polymerase III subunit theta -
JG797_RS17225 3478665..3479324 + 660 WP_002911407.1 exodeoxyribonuclease X -
JG797_RS17230 3479328..3481388 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T185431 NZ_CP066915:c3476482-3476380 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT185431 NZ_CP066915:3476373-3476518 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References