Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2033394..2033539 Replicon chromosome
Accession NZ_CP066910
Organism Klebsiella pneumoniae strain XHKPN083

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2033430..2033532 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2033394..2033539 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG792_RS09955 2028524..2030584 + 2061 WP_004151449.1 oligopeptidase B -
JG792_RS09960 2030588..2031247 - 660 WP_002911407.1 exodeoxyribonuclease X -
JG792_RS09965 2031326..2031556 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JG792_RS09970 2031669..2032043 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JG792_RS09975 2032047..2032916 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
JG792_RS09980 2032933..2033271 + 339 WP_002911404.1 YebY family protein -
- 2033394..2033539 - 146 - - Antitoxin
- 2033430..2033532 + 103 - - Toxin
JG792_RS09985 2033907..2034050 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JG792_RS09990 2034155..2035123 - 969 WP_004151446.1 VirK/YbjX family protein -
JG792_RS09995 2035280..2035933 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JG792_RS10000 2035930..2036121 - 192 WP_002911395.1 YebW family protein -
JG792_RS10005 2036219..2036458 - 240 WP_002911393.1 YebV family protein -
JG792_RS10010 2036574..2038007 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T185396 NZ_CP066910:2033430-2033532 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT185396 NZ_CP066910:c2033539-2033394 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References