Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2025212..2025357 Replicon chromosome
Accession NZ_CP066900
Organism Klebsiella pneumoniae strain XHKP309

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2025248..2025350 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2025212..2025357 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG788_RS09900 2020342..2022402 + 2061 WP_004151449.1 oligopeptidase B -
JG788_RS09905 2022406..2023065 - 660 WP_002911407.1 exodeoxyribonuclease X -
JG788_RS09910 2023144..2023374 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JG788_RS09915 2023487..2023861 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JG788_RS09920 2023865..2024734 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
JG788_RS09925 2024751..2025089 + 339 WP_002911404.1 YebY family protein -
- 2025212..2025357 - 146 - - Antitoxin
- 2025248..2025350 + 103 - - Toxin
JG788_RS09930 2025725..2025868 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JG788_RS09935 2025973..2026941 - 969 WP_004151446.1 VirK/YbjX family protein -
JG788_RS09940 2027098..2027751 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JG788_RS09945 2027748..2027939 - 192 WP_002911395.1 YebW family protein -
JG788_RS09950 2028037..2028276 - 240 WP_002911393.1 YebV family protein -
JG788_RS09955 2028392..2029825 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T185343 NZ_CP066900:2025248-2025350 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT185343 NZ_CP066900:c2025357-2025212 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References