Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2039290..2039435 Replicon chromosome
Accession NZ_CP066895
Organism Klebsiella pneumoniae strain XHKP75

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2039326..2039428 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2039290..2039435 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG785_RS09975 2034420..2036480 + 2061 WP_004151449.1 oligopeptidase B -
JG785_RS09980 2036484..2037143 - 660 WP_002911407.1 exodeoxyribonuclease X -
JG785_RS09985 2037222..2037452 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JG785_RS09990 2037565..2037939 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JG785_RS09995 2037943..2038812 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
JG785_RS10000 2038829..2039167 + 339 WP_002911404.1 YebY family protein -
- 2039290..2039435 - 146 - - Antitoxin
- 2039326..2039428 + 103 - - Toxin
JG785_RS10005 2039803..2039946 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JG785_RS10010 2040051..2041019 - 969 WP_004151446.1 VirK/YbjX family protein -
JG785_RS10015 2041176..2041829 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JG785_RS10020 2041826..2042017 - 192 WP_002911395.1 YebW family protein -
JG785_RS10025 2042115..2042354 - 240 WP_002911393.1 YebV family protein -
JG785_RS10030 2042470..2043903 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T185316 NZ_CP066895:2039326-2039428 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT185316 NZ_CP066895:c2039435-2039290 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References