Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2010881..2011026 Replicon chromosome
Accession NZ_CP066891
Organism Klebsiella pneumoniae strain XHKP53

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2010917..2011019 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2010881..2011026 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG783_RS09855 2006011..2008071 + 2061 WP_004151449.1 oligopeptidase B -
JG783_RS09860 2008075..2008734 - 660 WP_002911407.1 exodeoxyribonuclease X -
JG783_RS09865 2008813..2009043 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JG783_RS09870 2009156..2009530 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JG783_RS09875 2009534..2010403 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
JG783_RS09880 2010420..2010758 + 339 WP_002911404.1 YebY family protein -
- 2010881..2011026 - 146 - - Antitoxin
- 2010917..2011019 + 103 - - Toxin
JG783_RS09885 2011394..2011537 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JG783_RS09890 2011642..2012610 - 969 WP_004151446.1 VirK/YbjX family protein -
JG783_RS09895 2012767..2013420 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JG783_RS09900 2013417..2013608 - 192 WP_002911395.1 YebW family protein -
JG783_RS09905 2013706..2013945 - 240 WP_002911393.1 YebV family protein -
JG783_RS09910 2014061..2015494 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T185289 NZ_CP066891:2010917-2011019 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT185289 NZ_CP066891:c2011026-2010881 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References