Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2281223..2281494 Replicon chromosome
Accession NZ_CP066839
Organism Escherichia coli strain Ec-RL2-1X

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2281353..2281456 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2281223..2281494 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH656_RS11120 2277779..2278441 - 663 WP_000944256.1 exodeoxyribonuclease X -
JH656_RS11125 2278465..2279121 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
JH656_RS11130 2279223..2279453 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JH656_RS11135 2279592..2279966 + 375 WP_000255065.1 CopC domain-containing protein YobA -
JH656_RS11140 2279970..2280842 + 873 WP_000879294.1 copper homeostasis membrane protein CopD -
JH656_RS11145 2280855..2281196 + 342 WP_000976472.1 YebY family protein -
- 2281223..2281494 - 272 - - Antitoxin
- 2281353..2281456 + 104 - - Toxin
JH656_RS11150 2281591..2282247 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
JH656_RS11155 2282248..2282439 - 192 WP_001296140.1 YebW family protein -
JH656_RS11160 2282544..2282780 - 237 WP_001295499.1 YebV family protein -
JH656_RS11165 2282898..2284337 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T185176 NZ_CP066839:2281353-2281456 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT185176 NZ_CP066839:c2281494-2281223 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References