Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1945219..1945453 | Replicon | chromosome |
| Accession | NZ_CP066809 | ||
| Organism | Shigella flexneri 3a strain 888048 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1945349..1945452 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1945219..1945453 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JGY96_RS09730 | 1941774..1942436 | - | 663 | WP_000944269.1 | exodeoxyribonuclease X | - |
| JGY96_RS09735 | 1942460..1943116 | - | 657 | WP_000011667.1 | carbon-nitrogen hydrolase family protein YobB | - |
| JGY96_RS09740 | 1943218..1943448 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| JGY96_RS09745 | 1943587..1943961 | + | 375 | WP_025758141.1 | CopC domain-containing protein YobA | - |
| JGY96_RS09750 | 1943965..1944837 | + | 873 | Protein_1899 | copper homeostasis membrane protein CopD | - |
| JGY96_RS09755 | 1944850..1945191 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 1945219..1945453 | - | 235 | - | - | Antitoxin |
| - | 1945349..1945452 | + | 104 | - | - | Toxin |
| JGY96_RS09760 | 1945584..1946660 | - | 1077 | WP_025758140.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| JGY96_RS09765 | 1946626..1946907 | - | 282 | WP_005127484.1 | excisionase | - |
| JGY96_RS09770 | 1947024..1948173 | - | 1150 | Protein_1903 | IS3 family transposase | - |
| JGY96_RS09775 | 1948243..1948623 | + | 381 | Protein_1904 | IS66-like element accessory protein TnpA | - |
| JGY96_RS09780 | 1948625..1948792 | + | 168 | Protein_1905 | phage tail protein | - |
| JGY96_RS09785 | 1948743..1949364 | + | 622 | Protein_1906 | DUF4376 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | fliA / ipaH9.8 / ipaH9.8 | 1846404..2008267 | 161863 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T185104 NZ_CP066809:1945349-1945452 [Shigella flexneri 3a]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT185104 NZ_CP066809:c1945453-1945219 [Shigella flexneri 3a]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT
