Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 1332847..1333582 Replicon chromosome
Accession NZ_CP066803
Organism Pantoea ananatis strain LCFJ-001

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JGU81_RS06020 Protein ID WP_022623268.1
Coordinates 1332847..1333239 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JGU81_RS06025 Protein ID WP_014605595.1
Coordinates 1333229..1333582 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JGU81_RS06005 1328143..1329315 - 1173 WP_013026120.1 FMNH2-dependent alkanesulfonate monooxygenase -
JGU81_RS06010 1329594..1331480 + 1887 WP_181134487.1 aliphatic sulfonate ABC transporter substrate-binding protein -
JGU81_RS06015 1331575..1332522 + 948 WP_200286903.1 sulfonate ABC transporter substrate-binding protein -
JGU81_RS06020 1332847..1333239 + 393 WP_022623268.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JGU81_RS06025 1333229..1333582 + 354 WP_014605595.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
JGU81_RS06040 1334133..1334672 - 540 WP_014605653.1 peptide-methionine (S)-S-oxide reductase MsrA -
JGU81_RS06045 1335035..1336102 - 1068 WP_013026114.1 two-component system sensor histidine kinase PmrB -
JGU81_RS06050 1336099..1336785 - 687 WP_014593911.1 two-component system response regulator PmrA -
JGU81_RS06055 1337671..1338459 + 789 WP_089517295.1 trehalose-phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(6-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(56-99)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14981.30 Da        Isoelectric Point: 10.1741

>T185049 WP_022623268.1 NZ_CP066803:1332847-1333239 [Pantoea ananatis]
MGFTLYVHKRFDRVFKKTRLTDSVLCYAAGDVITGVFEADLGGGVIKKRLALHQGKRGGVRTVIFFRQGTNLVYYDGWVK
NLSRKYAREIDEDQLDTYRDVARMFFRANSEVMSLLVRSGMVREVKCNEN

Download         Length: 393 bp

>T185049 NZ_CP087952:749207-749425 [Desulfosarcina sp. BuS5]
TTGCCTAATGATATTCAGAGGCTTGCTGAGTGTAAGCTGGTTATGCTTCATAATGCCGGAGGCATTAACGACCTTCGGGT
TCCTCCTGCCAACCGGCTGGAAGCATTAAGGGGAACAAGGAAGGGGCGGCACAGTATTCGAATTAATGATCAGTGGCGTA
TTTGTTTTAAATGGCGTGCTGATGGCGTATATCATGTTGAAATAACAGATTATCATTGA

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 13096.14 Da        Isoelectric Point: 7.2076

>AT185049 WP_014605595.1 NZ_CP066803:1333229-1333582 [Pantoea ananatis]
MKTEPAELSELLEDAKAFHALGLATDEEVESIAKRAKNRELRARIASVKPMTATEIKDVRMRWGMSQSLVALSFGMTVDS
VSKWERGEITPSPPVMRMLQLLRDNGPELFTSKHQGI

Download         Length: 354 bp

>AT185049 NZ_CP087952:749434-749733 [Desulfosarcina sp. BuS5]
ATGAGAGATTTTCCACCGGTTCATCCTGGTGAAATCCTGCTTGAGGAATTTTTAAAACCTATGGGAATTAGTCAATATCG
CCTTGCAAAAGATATAGGTGTCGCGGCTATGCGTATCAACAAAATTGTTCGCGGCAAAAGGGGAATCAGCGCGGATACGG
CGCTTCGCCTTGCCCGCTATTTTGGAATGTCGGTTGAATTCTGGACAGGAATCCAGACTCATTATGAGACTGAAATGGCT
AAAATGGTACTCGCAGGCCGGCTTGAGAAGGAAGTAAAAATTTTTGCGCAAGCCGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References