Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 102579..103174 Replicon plasmid unnamed2
Accession NZ_CP066790
Organism Burkholderia glumae strain FDAARGOS_921

Toxin (Protein)


Gene name chpB Uniprot ID C5AN78
Locus tag I6G78_RS01420 Protein ID WP_012734107.1
Coordinates 102824..103174 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID C5AN79
Locus tag I6G78_RS01415 Protein ID WP_012734108.1
Coordinates 102579..102830 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G78_RS01380 97848..98036 + 189 WP_017432455.1 hypothetical protein -
I6G78_RS01385 98788..99072 + 285 WP_017432347.1 hypothetical protein -
I6G78_RS01390 99086..99328 + 243 WP_124837682.1 hypothetical protein -
I6G78_RS01395 99325..99570 + 246 WP_127913916.1 hypothetical protein -
I6G78_RS01400 99627..99968 + 342 WP_012732710.1 hypothetical protein -
I6G78_RS01405 99971..101806 + 1836 WP_045678669.1 site-specific integrase -
I6G78_RS01410 101891..102316 + 426 WP_012734109.1 hypothetical protein -
I6G78_RS01415 102579..102830 + 252 WP_012734108.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
I6G78_RS01420 102824..103174 + 351 WP_012734107.1 type II toxin-antitoxin system ChpB family toxin Toxin
I6G78_RS01425 103233..103427 + 195 WP_124837685.1 hypothetical protein -
I6G78_RS01430 103577..103798 + 222 WP_017433768.1 hypothetical protein -
I6G78_RS01435 104021..104485 + 465 WP_012734106.1 Lrp/AsnC family transcriptional regulator -
I6G78_RS01440 104787..107174 + 2388 WP_045678668.1 TonB-dependent receptor -
I6G78_RS01445 107164..107951 + 788 Protein_122 TonB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..144520 144520


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12389.37 Da        Isoelectric Point: 8.8909

>T185025 WP_012734107.1 NZ_CP066790:102824-103174 [Burkholderia glumae]
MVKRVKFERGDIVRVSLSPTVGREQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARFAGFAVPLSGSGTETQGVALV
NMVRMLDLEGRGARKIERAPVEVVEDALARLQTIIE

Download         Length: 351 bp

>T185025 NZ_CP087880:905722-905824 [Pseudocitrobacter corydidari]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8940.31 Da        Isoelectric Point: 6.2420

>AT185025 WP_012734108.1 NZ_CP066790:102579-102830 [Burkholderia glumae]
MELKIQKWGNSAAVRLPSVLLEQINASVGGSLNADVRPDGVLLTPARRKYALDDLVAQCDTKAPVPADMAAWGEIKPVGR
EAW

Download         Length: 252 bp

>AT185025 NZ_CP087880:c905830-905686 [Pseudocitrobacter corydidari]
ACTGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGATGACCGTGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A246MF70

Antitoxin

Source ID Structure
AlphaFold DB A0A246MFN5

References