Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1846197..1846870 Replicon chromosome
Accession NZ_CP066786
Organism Martelella lutilitoris strain ZRK001

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JET14_RS08705 Protein ID WP_200337665.1
Coordinates 1846448..1846870 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JET14_RS08700 Protein ID WP_200337664.1
Coordinates 1846197..1846451 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JET14_RS08670 1841854..1842303 - 450 WP_200337662.1 DUF892 family protein -
JET14_RS08675 1842413..1843000 - 588 WP_200337663.1 cysteine hydrolase -
JET14_RS08680 1843265..1843888 - 624 Protein_1710 YdiU family protein -
JET14_RS08685 1844012..1844882 + 871 Protein_1711 nitronate monooxygenase -
JET14_RS08690 1845012..1845274 - 263 Protein_1712 pyocin activator PrtN family protein -
JET14_RS08695 1845246..1846013 + 768 Protein_1713 chromosome partitioning protein ParB -
JET14_RS08700 1846197..1846451 + 255 WP_200337664.1 plasmid stabilization protein Antitoxin
JET14_RS08705 1846448..1846870 + 423 WP_200337665.1 type II toxin-antitoxin system VapC family toxin Toxin
JET14_RS08710 1846934..1847317 - 384 WP_200337666.1 phosphotransferase -
JET14_RS08715 1847375..1848565 + 1191 WP_200337667.1 transposase -
JET14_RS08720 1848743..1849123 + 381 WP_200337668.1 hypothetical protein -
JET14_RS08725 1849120..1849974 + 855 WP_200337669.1 hypothetical protein -
JET14_RS08730 1849974..1850618 + 645 WP_200337670.1 DUF4376 domain-containing protein -
JET14_RS08735 1850623..1850889 + 267 WP_200337671.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14904.96 Da        Isoelectric Point: 4.8837

>T185021 WP_200337665.1 NZ_CP066786:1846448-1846870 [Martelella lutilitoris]
MIVLDTNVVSEAMKPEPDLAVRDWLDEQAAETLYISSVTVAELLFGIGALPEGRRKQKLAATLDGMLPLFEGRILAFDSN
AARHYADLAVAARKAGRGFPTPDGYIGAIATAHGFAVATRDASAFDAAGVPVIDPWNARH

Download         Length: 423 bp

>T185021 NZ_CP087865:c1915290-1914889 [Moraxella bovis]
ATGTTTAGTTTTATGCTGGATACCAATATCTGCATTTATGTGATAAAAGAACGCCCCATAAAAGCATTAAACAAATTTAA
CCAATATGCAGGGCGGATTTGCGTAAGCAGTATCGTGGCAAGCGAGTTGTATTTTGGGGCATACAACAGCCAATTTATGG
ATAAAAATCTACATCAAGTCGAAGATTTTTTATCACGTTTGACGGTGCTTGATTATACCGCAGAATGCTCGCCCCATTAC
GGCGAGATTTGTGCTGATTTGACCAAGCAGGGCAAGCTCATTAGTGAAAATGACATTCATATCGCCTCTCATGCACGGGC
ATTGGGGCTGACCTTGATTACCAATAATACCGATGAATTTAAACGAGTGTCAGGGCTTAGGATTGGTAATTGGGCGATTT
GA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9115.34 Da        Isoelectric Point: 10.4420

>AT185021 WP_200337664.1 NZ_CP066786:1846197-1846451 [Martelella lutilitoris]
MPAVTIRNLSDETHRALKVRAAQHGRSAEAEMRDILESAVRPAERLRLGSALSALSRKAGLTNADFGALEQARDKTPATP
MSFE

Download         Length: 255 bp

>AT185021 NZ_CP087865:c1915538-1915305 [Moraxella bovis]
ATGCAAACCAGTGTTTTTTTTAATAATCGCACCCAAGCGGTTCGCATTCCTGCCAAATTTCGCTTTGATGACGATGTCAA
AGCCGTCATGATTAGAAAAGTGGGCAATGAGCGGATTTTGACCCCAATTGATGGTGTGTGGGACAGCTTTTTTTTGAGTG
ATGAGCGAGCGAGTGATGATTTTATGGCAAACCGCCCGACCATGCCAAAAAGCGAGCGATTGACTTTTGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References