185016

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 1196896..1197524 Replicon chromosome
Accession NZ_CP066776
Organism Sulfuriroseicoccus oceanibius strain T37

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G3M56_RS04680 Protein ID WP_164365560.1
Coordinates 1196896..1197285 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G3M56_RS04685 Protein ID WP_164365561.1
Coordinates 1197282..1197524 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3M56_RS04660 (G3M56_004670) 1192631..1193080 + 450 WP_164365556.1 flavodoxin domain-containing protein -
G3M56_RS04665 (G3M56_004675) 1193159..1193548 + 390 WP_164365557.1 NINE protein -
G3M56_RS04670 (G3M56_004680) 1193870..1195354 + 1485 WP_164365558.1 glycerol kinase GlpK -
G3M56_RS04675 (G3M56_004685) 1195361..1196908 + 1548 WP_164365559.1 glycerol-3-phosphate dehydrogenase/oxidase -
G3M56_RS04680 (G3M56_004690) 1196896..1197285 - 390 WP_164365560.1 type II toxin-antitoxin system VapC family toxin Toxin
G3M56_RS04685 (G3M56_004695) 1197282..1197524 - 243 WP_164365561.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
G3M56_RS04690 (G3M56_004700) 1197560..1199584 - 2025 WP_235203591.1 sialidase family protein -
G3M56_RS04695 (G3M56_004705) 1199723..1200328 + 606 WP_164365562.1 flavin reductase family protein -
G3M56_RS04700 (G3M56_004710) 1200389..1200859 - 471 WP_164365563.1 transcription elongation factor -
G3M56_RS04705 (G3M56_004715) 1200877..1201431 - 555 WP_164365564.1 HNH endonuclease -
G3M56_RS04710 (G3M56_004720) 1201519..1202280 + 762 WP_164365565.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-44)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14487.56 Da        Isoelectric Point: 6.8427

>T185016 WP_164365560.1 NZ_CP066776:c1197285-1196896 [Sulfuriroseicoccus oceanibius]
MNRVLADTNIWCDFFSGGDSTLAHLLEYDLLLTHTLVIGELAVGNLPKRRQTLADLQQLPQMRSASFHETLTFINHHQLY
GRGLQWNDLLILASVIAAPGVLLWTRDRRLGAAAAEFNVAFDTPQHHSK

Download         Length: 390 bp

>T185016 NZ_CP087865:c640166-639939 [Moraxella bovis]
ATCTCTGAGCGAGCAGGTTCACGCATGGCTGTGGCGCTAAACGGGCAAGTCATGGTTTTTCATCGCCCACACCCAAGCCC
AAATACTGACAAAAGTGCGGTTATGAGCATTAGAAAATGGCTTGATGGCATGGGTATCACACCATTAGATGACGACAGCC
AAACAGACGAATACGCAGACAAACAAACCGACGAACAGGAGCAGACTCATGAACACAATGACAATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8455.54 Da        Isoelectric Point: 4.6321

>AT185016 WP_164365561.1 NZ_CP066776:c1197524-1197282 [Sulfuriroseicoccus oceanibius]
MRTTVTIDDELFAEAAKITGESSASPVINAALKALVAAESRKRLQALAGSAPGFTVPPRDQRSMPICVADDPQNYPSENP

Download         Length: 243 bp

>AT185016 NZ_CP087865:c639958-639623 [Moraxella bovis]
ATGAACACAATGACAATTAACAATCATAAAGCCTTAATCACTTTTGACAGTGAGTTAGGACTGTTTCGTGGGGAGTTTAT
CGGATTAAATGGCGGGGCAGATTTTTATGCTGACAGCGTAGATGGTCTCAATGAACAAGGGGCTTTATCCCTGCAAGCCT
TTTTAGATGTATGTCAAGAACAGGGCATTAGCCCTTATCAGTCGTACAGTGGCAAATTTGTCACACGCCTACCCAAAGAG
TTACATCAAAAAATCGCAGAAACTGCTACCGCCAAGGGTATTAGCCTAAACCAGTGGATTAATGAAACACTCAGCCGTGA
AGTTGGCTTTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References