Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 66249..66760 Replicon chromosome
Accession NZ_CP066776
Organism Sulfuriroseicoccus oceanibius strain T37

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G3M56_RS00265 Protein ID WP_164364887.1
Coordinates 66249..66503 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag G3M56_RS00270 Protein ID WP_235203494.1
Coordinates 66500..66760 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3M56_RS00245 (G3M56_000245) 61386..61766 - 381 WP_164364896.1 hypothetical protein -
G3M56_RS00250 (G3M56_000250) 61998..64718 + 2721 WP_164364893.1 valine--tRNA ligase -
G3M56_RS00255 (G3M56_000255) 64831..65256 + 426 WP_164364891.1 BLUF domain-containing protein -
G3M56_RS00260 (G3M56_000260) 65602..66234 + 633 WP_164364889.1 hypothetical protein -
G3M56_RS00265 (G3M56_000265) 66249..66503 - 255 WP_164364887.1 Txe/YoeB family addiction module toxin Toxin
G3M56_RS00270 (G3M56_000270) 66500..66760 - 261 WP_235203494.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G3M56_RS00275 (G3M56_000275) 66886..67869 - 984 WP_164364883.1 MDR family oxidoreductase -
G3M56_RS00280 (G3M56_000280) 68001..68144 + 144 WP_164364880.1 hypothetical protein -
G3M56_RS00285 (G3M56_000285) 68141..69043 - 903 WP_164364877.1 pantoate--beta-alanine ligase -
G3M56_RS00290 (G3M56_000290) 69152..70777 - 1626 WP_164364875.1 murein biosynthesis integral membrane protein MurJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-76)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10358.85 Da        Isoelectric Point: 9.9582

>T185015 WP_164364887.1 NZ_CP066776:c66503-66249 [Sulfuriroseicoccus oceanibius]
MRKVFSDQAWEDYLHWQKTDKRMLRKVNDLIKDIDRNLHEGIGKPEPLKHRLAGYWSRRINAEHRLVYRIDEGEIQIAQI
RYHY

Download         Length: 255 bp

>T185015 NZ_CP087865:361087-361479 [Moraxella bovis]
ATGAAATATTTGCTGGACACCAATGCAGTCATTGCGATTTTGAATGCCAGTGAACGATTTTTGACCACGCTAGAACGGCA
TAAAGAGCGTGAAATTGCCATCTCGTCAATTGTTTTGTCGGAGCTGTATTATGGGGCGTACAAAAGCCAAAAAACCGCCC
AAAACCTTGAAAAAATCAATCTACTACCCTTTGAAGTGTTGCAATTTAATTCACAGGACGCTGATAAGGCTGGCGAAATT
GGTGCAACCCTAGAAAGGCGTGGCACACCCATTGGTTCTTATGACACGCTGATTGCAGGGCAAGCGATTGCCAATGATTT
GATTGTTATTACTGACAATGTGCGAGAATTTCTCCGAGTGGACGGTTTGCAAATTGAAAATTGGTTAAAATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9698.16 Da        Isoelectric Point: 8.0442

>AT185015 WP_235203494.1 NZ_CP066776:c66760-66500 [Sulfuriroseicoccus oceanibius]
MYNMKAVTYSHARAHLARTISEVCENHDPVVITKKGTDSVVMMSLEDYESMQETAYLLRSPKNASRLLLSLEQLESGKGK
ERPLAK

Download         Length: 261 bp

>AT185015 NZ_CP087865:360827-361090 [Moraxella bovis]
ATGCGCCAAACTGCCACCGCAAAATTATTTTGGACTGGCAACAGTCAAGCCGTTCGCTTACCCAAAGCCTTTCGTTTTGA
AGGCACGGAAGTGCGTATCAAAAAACAAGGACGACAAGTGATTATTGAGCCAGCAGAGACCCAAGATTGGGCGTGGCTGG
ACAAATTGCGAGCAATGCCAAAAGATGACAGTTTTGAAGAAGCCATTTTGGAAGGTCGCCAAAATTTAAAAGCCGATGAA
CGAGATTGGGGTGCATTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References