Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 1786206..1786888 Replicon chromosome
Accession NZ_CP066769
Organism Burkholderia anthina strain BJQ0011

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag JFN94_RS08365 Protein ID WP_175750849.1
Coordinates 1786466..1786888 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag JFN94_RS08360 Protein ID WP_175750848.1
Coordinates 1786206..1786469 (+) Length 88 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JFN94_RS08345 1781752..1784007 + 2256 WP_124825733.1 TonB-dependent siderophore receptor -
JFN94_RS08350 1784094..1784933 + 840 WP_124825732.1 N(5)-hydroxyornithine transformylase PvdF -
JFN94_RS08355 1784933..1785955 + 1023 WP_124825731.1 acetyltransferase -
JFN94_RS08360 1786206..1786469 + 264 WP_175750848.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
JFN94_RS08365 1786466..1786888 + 423 WP_175750849.1 type II toxin-antitoxin system VapC family toxin Toxin
JFN94_RS08370 1787242..1788147 - 906 WP_175750850.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
JFN94_RS08375 1788116..1789186 - 1071 WP_124825978.1 hypothetical protein -
JFN94_RS08380 1789546..1790709 + 1164 WP_124825728.1 amidohydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-126)

Antitoxin

(7-38)


Sequences


Toxin        


Download         Length: 141 a.a.        Molecular weight: 14714.86 Da        Isoelectric Point: 8.5394

>T185005 WP_175750849.1 NZ_CP066769:1786466-1786888 [Burkholderia anthina]
VTTLYMLDTNIRSFIMRERPPVALSRLQSCVNAQHRIVVSAITYAEMRFGAVGKKASPRHAELVTAFVARLDGVLSWDTA
AVDATTAVRAGLAARGTPIGANDASIAGHAIAAGAVLVTNNSREFSCVAGLSVEDWAMSA

Download         Length: 423 bp

>T185005 NZ_CP087863:358186-358458 [Moraxella bovis]
GTGGCTAAACGTAGTTTTGAAATGGGCAATCCCTTTAAAAGGGATTTAAAAAAGCATTATTTGGCATTGATTGGCGAAGC
GTGGACGGAAGTGTCTGATTGCTTGTTAAATGCCAAACCCATACCTCAAAAATACCAAGACCACCCATTGCAAGGCGATT
GGGTGGGGTTTAGAGATTGTCATATCAAGCCTGATTTGGTGCTAATTTATAAAATAAATGATGAAGCGGTGGAATTACAT
CGGCTTGCCACGCATAGCGAGTTGTTTGGTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9759.91 Da        Isoelectric Point: 4.5098

>AT185005 WP_175750848.1 NZ_CP066769:1786206-1786469 [Burkholderia anthina]
MRTVSIFKTARNQAIRIPKDMEFEGVTELEIRREGDTLLRPGRPTWLSFANEPLADSDFLIERPAVVETGRFDLSGADHD
ASPESGQ

Download         Length: 264 bp

>AT185005 NZ_CP087863:357900-358193 [Moraxella bovis]
ATGAGCCACACCAATTTTAATATGCGACTAGACAACGACCTACGCCAAAAAGTCTATCCTGTGCTAGAACAATACGGCTT
GACCCCAAGCCAAGCAGTGCGGATGTTTTTTAATCAAATCGCCCAAACAGGCAAAGTGCCATTGTCTTTTGATTGGGGGC
AGTCGCATACGCTTAGTAGCAATGGCGAAAAGCTGTTGCGTGAGAGTATTCAAGCTTTTGAAAATGGCGAAACCGAGCGA
TTTGATAGCTTAGATGAGTTAAATCAAGCAATGGCGGAGATTGCTCGTGGCTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References