Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vagCD/VapC-VagC |
Location | 1786206..1786888 | Replicon | chromosome |
Accession | NZ_CP066769 | ||
Organism | Burkholderia anthina strain BJQ0011 |
Toxin (Protein)
Gene name | vagD | Uniprot ID | - |
Locus tag | JFN94_RS08365 | Protein ID | WP_175750849.1 |
Coordinates | 1786466..1786888 (+) | Length | 141 a.a. |
Antitoxin (Protein)
Gene name | vagC | Uniprot ID | - |
Locus tag | JFN94_RS08360 | Protein ID | WP_175750848.1 |
Coordinates | 1786206..1786469 (+) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JFN94_RS08345 | 1781752..1784007 | + | 2256 | WP_124825733.1 | TonB-dependent siderophore receptor | - |
JFN94_RS08350 | 1784094..1784933 | + | 840 | WP_124825732.1 | N(5)-hydroxyornithine transformylase PvdF | - |
JFN94_RS08355 | 1784933..1785955 | + | 1023 | WP_124825731.1 | acetyltransferase | - |
JFN94_RS08360 | 1786206..1786469 | + | 264 | WP_175750848.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
JFN94_RS08365 | 1786466..1786888 | + | 423 | WP_175750849.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
JFN94_RS08370 | 1787242..1788147 | - | 906 | WP_175750850.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
JFN94_RS08375 | 1788116..1789186 | - | 1071 | WP_124825978.1 | hypothetical protein | - |
JFN94_RS08380 | 1789546..1790709 | + | 1164 | WP_124825728.1 | amidohydrolase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 141 a.a. Molecular weight: 14714.86 Da Isoelectric Point: 8.5394
>T185005 WP_175750849.1 NZ_CP066769:1786466-1786888 [Burkholderia anthina]
VTTLYMLDTNIRSFIMRERPPVALSRLQSCVNAQHRIVVSAITYAEMRFGAVGKKASPRHAELVTAFVARLDGVLSWDTA
AVDATTAVRAGLAARGTPIGANDASIAGHAIAAGAVLVTNNSREFSCVAGLSVEDWAMSA
VTTLYMLDTNIRSFIMRERPPVALSRLQSCVNAQHRIVVSAITYAEMRFGAVGKKASPRHAELVTAFVARLDGVLSWDTA
AVDATTAVRAGLAARGTPIGANDASIAGHAIAAGAVLVTNNSREFSCVAGLSVEDWAMSA
Download Length: 423 bp
>T185005 NZ_CP087863:358186-358458 [Moraxella bovis]
GTGGCTAAACGTAGTTTTGAAATGGGCAATCCCTTTAAAAGGGATTTAAAAAAGCATTATTTGGCATTGATTGGCGAAGC
GTGGACGGAAGTGTCTGATTGCTTGTTAAATGCCAAACCCATACCTCAAAAATACCAAGACCACCCATTGCAAGGCGATT
GGGTGGGGTTTAGAGATTGTCATATCAAGCCTGATTTGGTGCTAATTTATAAAATAAATGATGAAGCGGTGGAATTACAT
CGGCTTGCCACGCATAGCGAGTTGTTTGGTTGA
GTGGCTAAACGTAGTTTTGAAATGGGCAATCCCTTTAAAAGGGATTTAAAAAAGCATTATTTGGCATTGATTGGCGAAGC
GTGGACGGAAGTGTCTGATTGCTTGTTAAATGCCAAACCCATACCTCAAAAATACCAAGACCACCCATTGCAAGGCGATT
GGGTGGGGTTTAGAGATTGTCATATCAAGCCTGATTTGGTGCTAATTTATAAAATAAATGATGAAGCGGTGGAATTACAT
CGGCTTGCCACGCATAGCGAGTTGTTTGGTTGA
Antitoxin
Download Length: 88 a.a. Molecular weight: 9759.91 Da Isoelectric Point: 4.5098
>AT185005 WP_175750848.1 NZ_CP066769:1786206-1786469 [Burkholderia anthina]
MRTVSIFKTARNQAIRIPKDMEFEGVTELEIRREGDTLLRPGRPTWLSFANEPLADSDFLIERPAVVETGRFDLSGADHD
ASPESGQ
MRTVSIFKTARNQAIRIPKDMEFEGVTELEIRREGDTLLRPGRPTWLSFANEPLADSDFLIERPAVVETGRFDLSGADHD
ASPESGQ
Download Length: 264 bp
>AT185005 NZ_CP087863:357900-358193 [Moraxella bovis]
ATGAGCCACACCAATTTTAATATGCGACTAGACAACGACCTACGCCAAAAAGTCTATCCTGTGCTAGAACAATACGGCTT
GACCCCAAGCCAAGCAGTGCGGATGTTTTTTAATCAAATCGCCCAAACAGGCAAAGTGCCATTGTCTTTTGATTGGGGGC
AGTCGCATACGCTTAGTAGCAATGGCGAAAAGCTGTTGCGTGAGAGTATTCAAGCTTTTGAAAATGGCGAAACCGAGCGA
TTTGATAGCTTAGATGAGTTAAATCAAGCAATGGCGGAGATTGCTCGTGGCTAA
ATGAGCCACACCAATTTTAATATGCGACTAGACAACGACCTACGCCAAAAAGTCTATCCTGTGCTAGAACAATACGGCTT
GACCCCAAGCCAAGCAGTGCGGATGTTTTTTAATCAAATCGCCCAAACAGGCAAAGTGCCATTGTCTTTTGATTGGGGGC
AGTCGCATACGCTTAGTAGCAATGGCGAAAAGCTGTTGCGTGAGAGTATTCAAGCTTTTGAAAATGGCGAAACCGAGCGA
TTTGATAGCTTAGATGAGTTAAATCAAGCAATGGCGGAGATTGCTCGTGGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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