Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2142918..2143189 Replicon chromosome
Accession NZ_CP066756
Organism Escherichia coli O157:H7 strain ECP19-798

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2143048..2143151 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2142918..2143189 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG530_RS10580 2139473..2140135 - 663 WP_000944243.1 exodeoxyribonuclease X -
JG530_RS10585 2140159..2140815 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
JG530_RS10590 2140917..2141147 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JG530_RS10595 2141286..2141660 + 375 WP_000168751.1 CopC domain-containing protein YobA -
JG530_RS10600 2141664..2142536 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
JG530_RS10605 2142549..2142890 + 342 WP_000976483.1 YebY family protein -
- 2142918..2143189 - 272 - - Antitoxin
- 2143048..2143151 + 104 - - Toxin
JG530_RS10610 2143286..2143942 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
JG530_RS10615 2143943..2144134 - 192 WP_001296140.1 YebW family protein -
JG530_RS10620 2144239..2144475 - 237 WP_001295499.1 DUF1480 family protein -
JG530_RS10625 2144593..2146032 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T184939 NZ_CP066756:2143048-2143151 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT184939 NZ_CP066756:c2143189-2142918 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References