Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2281204..2281475 Replicon chromosome
Accession NZ_CP066753
Organism Escherichia coli O157:H7 strain ECP19-598

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2281334..2281437 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2281204..2281475 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG531_RS11485 2277759..2278421 - 663 WP_000944243.1 exodeoxyribonuclease X -
JG531_RS11490 2278445..2279101 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
JG531_RS11495 2279203..2279433 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JG531_RS11500 2279572..2279946 + 375 WP_000168751.1 CopC domain-containing protein YobA -
JG531_RS11505 2279950..2280822 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
JG531_RS11510 2280835..2281176 + 342 WP_000976483.1 YebY family protein -
- 2281204..2281475 - 272 - - Antitoxin
- 2281334..2281437 + 104 - - Toxin
JG531_RS11515 2281572..2282228 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
JG531_RS11520 2282229..2282420 - 192 WP_001296140.1 YebW family protein -
JG531_RS11525 2282525..2282761 - 237 WP_001295499.1 DUF1480 family protein -
JG531_RS11530 2282879..2284318 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T184899 NZ_CP066753:2281334-2281437 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT184899 NZ_CP066753:c2281475-2281204 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References