Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2253644..2253915 Replicon chromosome
Accession NZ_CP066748
Organism Escherichia coli O157:H7 strain ECP19-2498

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2253774..2253877 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2253644..2253915 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG532_RS11340 2250199..2250861 - 663 WP_000944243.1 exodeoxyribonuclease X -
JG532_RS11345 2250885..2251541 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
JG532_RS11350 2251643..2251873 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JG532_RS11355 2252012..2252386 + 375 WP_000168751.1 CopC domain-containing protein YobA -
JG532_RS11360 2252390..2253262 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
JG532_RS11365 2253275..2253616 + 342 WP_000976483.1 YebY family protein -
- 2253644..2253915 - 272 - - Antitoxin
- 2253774..2253877 + 104 - - Toxin
JG532_RS11370 2254012..2254668 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
JG532_RS11375 2254669..2254860 - 192 WP_001296140.1 YebW family protein -
JG532_RS11380 2254965..2255201 - 237 WP_001295499.1 DUF1480 family protein -
JG532_RS11385 2255319..2256758 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T184859 NZ_CP066748:2253774-2253877 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT184859 NZ_CP066748:c2253915-2253644 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References