Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1105650..1106455 Replicon chromosome
Accession NZ_CP066721
Organism Staphylococcus xylosus strain 2.1523

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag JGY88_RS05315 Protein ID WP_251481588.1
Coordinates 1106282..1106455 (+) Length 58 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag JGY88_RS05310 Protein ID WP_101104111.1
Coordinates 1105650..1106249 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JGY88_RS05290 (1101521) 1101521..1102987 + 1467 WP_101104109.1 ABC transporter substrate-binding protein/permease -
JGY88_RS05295 (1102980) 1102980..1103702 + 723 WP_042362430.1 amino acid ABC transporter ATP-binding protein -
JGY88_RS05300 (1103865) 1103865..1104995 + 1131 WP_101104110.1 tRNA epoxyqueuosine(34) reductase QueG -
JGY88_RS05305 (1104997) 1104997..1105467 + 471 WP_029376880.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
JGY88_RS05310 (1105650) 1105650..1106249 + 600 WP_101104111.1 glucosamine-6-phosphate isomerase Antitoxin
JGY88_RS05315 (1106282) 1106282..1106455 + 174 WP_251481588.1 SAS053 family protein Toxin
JGY88_RS05320 (1106703) 1106703..1107113 + 411 WP_101104113.1 hypothetical protein -
JGY88_RS05325 (1107343) 1107343..1108728 + 1386 WP_042362433.1 class II fumarate hydratase -
JGY88_RS05330 (1109084) 1109084..1109911 - 828 WP_107538384.1 RluA family pseudouridine synthase -
JGY88_RS05335 (1110102) 1110102..1111211 + 1110 WP_042362434.1 GAF domain-containing sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(126-195)


Sequences

Toxin        


Download         Length: 58 a.a.        Molecular weight: 6627.93 Da        Isoelectric Point: 3.6490

>T184827 WP_251481588.1 NZ_CP066721:1106282-1106455 [Staphylococcus xylosus]
MNSNKQQNESLEPENEMVDDFDDVVELGKEMEQISEENDEDKLDKSHDAEVRSDLND

Download         Length: 174 bp

>T184827 NZ_CP087817:c606882-606655 [Moraxella bovis]
ATCTCTGAGCGAGCAGGTTCACGCATGGCTGTGGCGCTAAACGGGCAAGTCATGGTTTTTCATCGCCCACACCCAAGCCC
AAATACTGACAAAAGTGCGGTTATGAGCATTAGAAAATGGCTTGATGGCATGGGTATCACACCATTAGATGACGACAGCC
AAACAGACGAATACGCAGACAAACAAACCGACGAACAGGAGCAGACTCATGAACACCATGACAATTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22336.29 Da        Isoelectric Point: 5.0042

>AT184827 WP_101104111.1 NZ_CP066721:1105650-1106249 [Staphylococcus xylosus]
MAMNFKVLENERVVAEYAADILRKQFNNNPTTIAGVHLANDNAPVLDELKKNVDKNAVDFSQINILDYDDKKSYFEALGV
PEGQIYNVSLSEDTESFIKDKIKTKENKGKLVTQVLSIDTKGNLDVSIKQGLFSAREVVLIITGSEKKEVVHKLYEENGK
TSFEPSDLKAHRMVNVILDEAAAEGLPEDVRHYFTARFA

Download         Length: 600 bp

>AT184827 NZ_CP087817:c606674-606339 [Moraxella bovis]
ATGAACACCATGACAATTAACAATCATAAAGCCTTAATCACTTTTGACAGTGAGTTAGGACTGTTTCGTGGGGAGTTTAT
CGGATTAAATGGCGGGGCAGATTTTTATGCTGACAGCGTAGATGGTCTCAATGAACAAGGGGCTTTATCCCTGCAAGCCT
TTTTAGATGTATGTCAAGAACAGGGCATTAGCCCTTATCAGTCGTACAGTGGCAAATTTGTCACACGCCTACCCAAAGAG
TTACATCAAAAAATCGCAGAAACTGCTACCGCCAAGGGTATTAGCCTAAACCAGTGGATTAATGAAACACTCAGCCGTGA
AGTTGGCTTTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References