184801

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 973378..974159 Replicon chromosome
Accession NZ_CP066712
Organism Staphylococcus pseudintermedius strain DSP027

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag JGZ40_RS04490 Protein ID WP_180291797.1
Coordinates 973998..974159 (+) Length 54 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag JGZ40_RS04485 Protein ID WP_233276620.1
Coordinates 973378..973977 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JGZ40_RS04465 (JGZ40_04420) 969251..970711 + 1461 WP_110159442.1 ABC transporter substrate-binding protein/permease -
JGZ40_RS04470 (JGZ40_04425) 970704..971429 + 726 WP_014613528.1 amino acid ABC transporter ATP-binding protein -
JGZ40_RS04475 (JGZ40_04430) 971585..972715 + 1131 WP_014613529.1 tRNA epoxyqueuosine(34) reductase QueG -
JGZ40_RS04480 (JGZ40_04435) 972715..973185 + 471 WP_014613530.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
JGZ40_RS04485 (JGZ40_04440) 973378..973977 + 600 WP_233276620.1 glucosamine-6-phosphate isomerase Antitoxin
JGZ40_RS04490 (JGZ40_04445) 973998..974159 + 162 WP_180291797.1 SAS053 family protein Toxin
JGZ40_RS04495 (JGZ40_04450) 974280..974723 + 444 WP_014613533.1 hypothetical protein -
JGZ40_RS04500 (JGZ40_04455) 974953..976338 + 1386 WP_110159441.1 class II fumarate hydratase -
JGZ40_RS04505 (JGZ40_04460) 976359..977884 + 1526 Protein_862 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(132-197)


Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 6228.71 Da        Isoelectric Point: 4.2450

>T184801 WP_180291797.1 NZ_CP066712:973998-974159 [Staphylococcus pseudintermedius]
MKDEQKHYDNEMVDSFDDVVELGKEMEQISEANDEEKLNQAHDSKVRSDKNTK

Download         Length: 162 bp

>T184801 NZ_CP087806:2187160-2187552 [Moraxella bovis]
ATGAAATATTTGCTGGACACCAATGCAGTCATTGCGATTTTGAATGCCAGTGAACGATTTTTGACCACGCTAGAACGGCA
TAAAGAGCGTGAAATTGCCATCTCGTCAATTGTTTTGTCGGAGCTGTATTATGGGGCGTACAAAAGCCAAAAAACCGCCC
AAAACCTTGAAAAAATCAATCTACTACCCTTTGAAGTGTTACAATTTAATTCACAGGACGCTGATAAGGCTGGCGAAATT
GGTGCAACCCTAGAAAGGCGTGGCACACCCATTGGTTCTTATGACACGCTGATTGCAGGGCAAGCGATTGCCAATGATTT
GATTGTTATTACTGACAATGTGCGAGAATTTCTCCGAGTGGACGGTTTGCAAATTGAAAATTGGTTAAAATAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22142.23 Da        Isoelectric Point: 6.0764

>AT184801 WP_233276620.1 NZ_CP066712:973378-973977 [Staphylococcus pseudintermedius]
MAMNFKVFKDAETAATFTADILRKQLNNNPTSIVGLHLNQEEAPVLDALKKDVDCHSVDFSQIHVLDYDAQQSYYQALGV
PEKQIHHVPEDEKVESFIKHHAKTKDNKGKLTLQVVTIDTKGQIGIPMNDALLPAREIIVVVTGAVKAEQVKKLYEENGN
TTFIPSALKSHRMVTVVLDEAAAQGLPEDVRNYFTSLYA

Download         Length: 600 bp

>AT184801 NZ_CP087806:2186900-2187163 [Moraxella bovis]
ATGCGCCAAACTGCCACCGCAAAATTATTTTGGACTGGCAACAGTCAAGCCGTTCGCTTACCCAAAGCCTTTCGTTTTGA
AGGCACGGAAGTGCGTATCAAAAAACAAGGACGACAAGTGATTATTGAGCCAGCAGAGACCCAAGATTGGGCGTGGCTGG
ACAAATTGCGAGCAATGCCAAAAGATGACAGTTTTGAAGAAGCCATTTTGGAAGGTCGCCAAAATTTAAAAGCCGATGAA
CGAGATTGGGGTGCATTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References