Detailed information of TA system TA184779

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 4036226..4037082
• Replicon: chromosome
• Accession: NZ_CP066699
• Organism: Rhodopseudomonas palustris strain RCB100

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: Q6N3W1
• Locus tag: I8G32_RS18445
• Protein ID: WP_011159121.1
• Coordinates: 4036226..4036756 (-)
• Length: 177 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: Q6N3W0
• Locus tag: I8G32_RS18450
• Protein ID: WP_011159122.1
• Coordinates: 4036744..4037082 (-)
• Length: 113 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I8G32_RS18425	4031452..4033452	+	2001	WP_011159117.1	phosphomethylpyrimidine synthase ThiC	-
I8G32_RS18430	4033623..4034498	+	876	WP_011159118.1	DUF4393 domain-containing protein	-
I8G32_RS18435	4034756..4035939	+	1184	WP_085977287.1	IS3-like element ISRpa2 family transposase	-
I8G32_RS18440	4035926..4036105	-	180	WP_011159120.1	hypothetical protein	-
I8G32_RS18445	4036226..4036756	-	531	WP_011159121.1	GNAT family N-acetyltransferase	Toxin
I8G32_RS18450	4036744..4037082	-	339	WP_011159122.1	DUF1778 domain-containing protein	Antitoxin
I8G32_RS18455	4037261..4038040	+	780	WP_011159123.1	hypothetical protein	-
I8G32_RS18460	4038228..4038740	-	513	WP_011159124.1	hypothetical protein	-
I8G32_RS18465	4039048..4039512	-	465	WP_011159125.1	hypothetical protein	-
I8G32_RS18470	4040710..4040994	+	285	WP_011159126.1	hypothetical protein	-
I8G32_RS18475	4041164..4041352	+	189	WP_042441214.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (50-151)

Antitoxin

• Vibrio phage ICP1, Orf50 (31-107)

Sequences

Toxin

Protein

• Length: 177 a.a.
• Molecular weight: 18929.60 Da
• Isoelectric Point: 7.7009

>T184779 WP_011159121.1 NZ_CP066699:c4036756-4036226 [Rhodopseudomonas palustris]
MADIDDAPNQPRSRLSAPVPLTIAHDLSAFDCGEPVLNDWLRQRALKNESRFSRTYVVCEGNQVVGYFCVSAGAVERAAA
PGKVRRNAPDAIPVSVIGRLAVSRSHAGIGLGADLLSDALRRIALASQSIGIGAVQVHAKDDAAKRFYLRCAEFIEYPQD
SRTLFLPIETVVAALS

Nucleotide

• Length: 531 bp

>T184779 NZ_CP087803:c2282209-2282021 [Moraxella bovis]
ATGCCCCCAAGTAGCGATGAGATGATAAAGCGAATTACCGAAGACGGTTGGTATTTTGTAAAACAAAAAGGCTCTCACAA
GCACTACAAACACCCAACCAAAGAAGGTAAAGTAACAATCCCAAACGGTCGTGAAAACCTACCCAAAGGAACGCTAAAAA
GCATCATCAAACAAGCAGGGTTGGATTAA

Antitoxin

Protein

• Length: 113 a.a.
• Molecular weight: 12160.97 Da
• Isoelectric Point: 11.4488

>AT184779 WP_011159122.1 NZ_CP066699:c4037082-4036744 [Rhodopseudomonas palustris]
MAKSRGAPAKSARRSAAAAARGATSDAKGSINLRIETGTRQLIDDAAAVLGKTRTEFMVESARRQAVDVLLDQRLFTLDP
ERYDAFMQALDNPPAPGPKLKALLRRVPAWRT

Nucleotide

• Length: 339 bp

>AT184779 NZ_CP087803:c2281958-2281551 [Moraxella bovis]
ATGTTATTTCCCATTGCCATTGAAAAACCTGCCAATGAAAACGAATGTTATGGCGTGATTGTGCCAGACATTGCAGGGTG
TTTTAGTGCAGGCGATACACCTGATGAAGCCATTAAGAATGCTTATGAAGCCATCAGTTTGCATTTGGAAGGCATGGCAG
AAGATGGCGATACACTACCTACCGCCAAGCCCATTTTTTATCATCAAGACAATAGCGAATTTGACGGTATGTTGTGGGCA
GTGGTGGACGTGGATATGTCTGCCTTTATGGGTAAGGCGGAGAAAATCAACGTTACCTTGCCAAGCCTACTCATCACCAA
AATTGACGAAAAAGTCTTGTCTCATAAATCGCTATACAAAAGCCGTTCTAATTATTTGGCACAATTGGCGATGGCAGATT
TGGGGTAG

Structures

Toxin

• AlphaFold DB: Q6N3W1

Antitoxin

• AlphaFold DB: Q6N3W0