Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3922209..3922864 Replicon chromosome
Accession NZ_CP066699
Organism Rhodopseudomonas palustris strain RCB100

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I8G32_RS17920 Protein ID WP_042441199.1
Coordinates 3922209..3922613 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I8G32_RS17925 Protein ID WP_042441643.1
Coordinates 3922610..3922864 (-) Length 85 a.a.

Genomic Context

I8G32_RS17910I8G32_RS17915I8G32_RS17905I8G32_RS17920I8G32_RS17925I8G32_RS17935I8G32_RS17940I8G32_RS17945
Location: 3917803..3919026 (1224 bp)
Type: Others
Protein ID: WP_011159022.1
Location: 3919029..3922166 (3138 bp)
Type: Others
Protein ID: WP_011159023.1
Location: 3917224..3917466 (243 bp)
Type: Others
Protein ID: WP_011159021.1
Location: 3922209..3922613 (405 bp)
Type: Toxin
Protein ID: WP_042441199.1
Location: 3922610..3922864 (255 bp)
Type: Antitoxin
Protein ID: WP_042441643.1
Location: 3923461..3924654 (1194 bp)
Type: Others
Protein ID: WP_011159025.1
Location: 3924764..3925975 (1212 bp)
Type: Others
Protein ID: WP_011159026.1
Location: 3926224..3926838 (615 bp)
Type: Others
Protein ID: WP_011159027.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I8G32_RS179053917224..3917466-243WP_011159021.1hypothetical protein-
I8G32_RS179103917803..3919026+1224WP_011159022.1efflux RND transporter periplasmic adaptor subunit-
I8G32_RS179153919029..3922166+3138WP_011159023.1multidrug efflux RND transporter permease subunit-
I8G32_RS179203922209..3922613-405WP_042441199.1PIN domain-containing proteinToxin
I8G32_RS179253922610..3922864-255WP_042441643.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
I8G32_RS179353923461..3924654-1194WP_011159025.1CoA transferase-
I8G32_RS179403924764..3925975-1212WP_011159026.1ABC transporter substrate-binding protein-
I8G32_RS179453926224..3926838-615WP_011159027.1class I SAM-dependent methyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-115)

Antitoxin

SpoVT-AbrB domain

(5-34)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14748.64 Da        Isoelectric Point: 5.8886

>T184778 WP_042441199.1 NZ_CP066699:c3922613-3922209 [Rhodopseudomonas palustris]
VRAFFDTNILVYSTTSDPRQATAAACLEQGGFASVQVLNEFVHVARRKLRHDWPQIEVALEQFHAALDDVLPITLTTHAA
AVVLARDHRVSFYDALIVAAAQAAGCDVLYSEDLQHGRTFGALRVENPFLEGSR

Download         Length: 405 bp

>T184778 NZ_CP087803:c2121597-2121196 [Moraxella bovis]
ATGTTTAGTTTTATGCTGGATACCAATATCTACATTTATGTGATAAAAGAACGCCCCATAAAAGCATTAAACAAATTTAA
CCAATATGCAGGGCGGATTTGCGTAAGCAGTATCGTGGCAAGCGAGTTGTATTTTGGGGCGTACAACAGCCAATTTATGG
ATAAAAATCTACATCAAGTCGAAGATTTTTTATCACGTTTGACGGTGCTTGATTATACCGCAGAATGCTCGCCCCATTAC
GGCGAGATTTGTGCTGATTTGACCAAGCAGGGCAAGCTCATTAGTGAAAATGACATTCATATCGCCTCTCATGCACGGGC
ATTGGGGCTGACCTTGATTACCAATAATACCGATGAATTTAAACGAGTGTCAGGGCTTAGGATTGGTAATTGGGCGATTT
GA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9900.21 Da        Isoelectric Point: 4.9534

>AT184778 WP_042441643.1 NZ_CP066699:c3922864-3922610 [Rhodopseudomonas palustris]
MLVSKWGNSLAVRLPKALVDKLDLKEGDELNVVDIVERTLVVEKEDRRKAAVERLSRLRWTLPTDYKFDRDEANERYRDE
SNEP

Download         Length: 255 bp

>AT184778 NZ_CP087803:c2121845-2121612 [Moraxella bovis]
ATGCAAACCAGTGTTTTTTTTAATAATCGCACCCAAGCGGTTCGCATTCCTGCCAAATTTCGCTTTGATGACGATGTCAA
AGCCGTCATGATTAGAAAAGTGGGCAATGAGCGGATTTTGACCCCAATTGATGGTGTGTGGGACAGCTTTTTTTTGAGTG
ATGAGCGAGCGAGTGATGATTTTATGGCAAACCGCCCGACCATGCCAAAAAGCGAGCGATTGACTTTTGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References