Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2232201..2232871 Replicon chromosome
Accession NZ_CP066699
Organism Rhodopseudomonas palustris strain RCB100

Toxin (Protein)


Gene name vapC Uniprot ID Q6N8B2
Locus tag I8G32_RS10195 Protein ID WP_011157547.1
Coordinates 2232201..2232611 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I8G32_RS10200 Protein ID WP_011157548.1
Coordinates 2232608..2232871 (-) Length 88 a.a.

Genomic Context

I8G32_RS10180I8G32_RS10185I8G32_RS10190I8G32_RS10205I8G32_RS10220I8G32_RS10225I8G32_RS10195I8G32_RS10200I8G32_RS10210I8G32_RS10215
Location: 2228590..2228916 (327 bp)
Type: Others
Protein ID: WP_011157544.1
Location: 2229083..2230873 (1791 bp)
Type: Others
Protein ID: WP_011157545.1
Location: 2230909..2231946 (1038 bp)
Type: Others
Protein ID: WP_042441504.1
Location: 2233052..2233477 (426 bp)
Type: Others
Protein ID: WP_011157549.1
Location: 2235638..2237029 (1392 bp)
Type: Others
Protein ID: WP_011157552.1
Location: 2237026..2237562 (537 bp)
Type: Others
Protein ID: WP_147408398.1
Location: 2232201..2232611 (411 bp)
Type: Toxin
Protein ID: WP_011157547.1
Location: 2232608..2232871 (264 bp)
Type: Antitoxin
Protein ID: WP_011157548.1
Location: 2233574..2234743 (1170 bp)
Type: Others
Protein ID: WP_011157550.1
Location: 2234929..2235237 (309 bp)
Type: Others
Protein ID: WP_011157551.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I8G32_RS101802228590..2228916+327WP_011157544.1hypothetical protein-
I8G32_RS101852229083..2230873+1791WP_011157545.1sulfatase-like hydrolase/transferase-
I8G32_RS101902230909..2231946+1038WP_042441504.1transporter-
I8G32_RS101952232201..2232611-411WP_011157547.1type II toxin-antitoxin system VapC family toxinToxin
I8G32_RS102002232608..2232871-264WP_011157548.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
I8G32_RS102052233052..2233477+426WP_011157549.1cupin domain-containing protein-
I8G32_RS102102233574..2234743-1170WP_011157550.1DUF2865 domain-containing protein-
I8G32_RS102152234929..2235237-309WP_011157551.1hypothetical protein-
I8G32_RS102202235638..2237029+1392WP_011157552.1cysteine--tRNA ligase-
I8G32_RS102252237026..2237562+537WP_147408398.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(9-58)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15136.48 Da        Isoelectric Point: 5.6802

>T184777 WP_011157547.1 NZ_CP066699:c2232611-2232201 [Rhodopseudomonas palustris]
MSGWMLDTNVASHVIRGDRREIIERLVALPISDVVISSITEGELLYGLAKRGYPTALSERVREFLLRVDVLPWDHEVTKT
YADLRAVCEAKGVTLSPLDMMIAAHAAATNATLVTRDKAFSRVPSPLRIEDWAEMS

Download         Length: 411 bp

>T184777 NZ_CP087803:c2017895-2017560 [Moraxella bovis]
ATGTGCGAATTAATGTATGAATTAGAATTTGACGAGCGAGCCTTAAAAGAATGGCAAAAACTGGGCGACACCATAAAAAC
GCAGTTTAAAAAGAGACTGGCTAAGGTGCTAAAAAATCCGCACATCATCGCCAATCGCCTAAGCGGTGGACAAAATTTAT
ACAAAATCAACTTCCGCTCGGCAGGTTATCGCCTTGTGTATCAAGTTGAAGATGATAAAGTGGTGGTGTTTGTCATCGTG
ATGGGTAAGCGTGAGAAAAATGCCGTCTATGACACCGCCGAAGAATGGCTTGCTGAACGTCAATCGGACAATCAAGACAC
ACAATCTGTCAAATAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9888.91 Da        Isoelectric Point: 4.7969

>AT184777 WP_011157548.1 NZ_CP066699:c2232871-2232608 [Rhodopseudomonas palustris]
VTSRTAKIFTTGRSQAVRLPAEFRFEGSEVFVRRDPRTGDVILSRKPDSWDGLLQLHQSADVPDDFLGPSDRSQLPQDRD
PFEGWTE

Download         Length: 264 bp

>AT184777 NZ_CP087803:c2018137-2017895 [Moraxella bovis]
ATGGCAAATATCGTGGCTCGTGTGGACGATGACCTAAAAGCCCAATCATTTTTGGTACTGCAAGAACTTGGCGTGACACC
GTCTGAGCTTATCCGCCAAACCTTGCAATATGTGGCTTATCACAAAAAATTACCCTTTAAGACGGTGGTTTTGACCGATG
AAGACAGTGAGCTTTTAGCCCTTGCCAAAGAACGCCTTGATAATCCTGCCCCACGCATCAAAGTCAGTTTGGACGAGCTT
TAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBQ6N8B2

Antitoxin

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Source
ID
Structure
No matching records found

References