Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 436798..437435 Replicon chromosome
Accession NZ_CP066567
Organism Histophilus somni strain ASc-MMNZ-VFA-079

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag JFL60_RS02285 Protein ID WP_011609928.1
Coordinates 436798..437034 (+) Length 79 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag JFL60_RS02290 Protein ID WP_011609927.1
Coordinates 437172..437435 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JFL60_RS02270 431909..435733 + 3825 WP_198986227.1 hemagglutinin repeat-containing protein -
JFL60_RS02275 436078..436332 + 255 WP_198986229.1 hypothetical protein -
JFL60_RS02280 436453..436722 + 270 WP_011609929.1 DUF1778 domain-containing protein -
JFL60_RS02285 436798..437034 + 237 WP_011609928.1 hypothetical protein Toxin
JFL60_RS02290 437172..437435 + 264 WP_011609927.1 DUF1778 domain-containing protein Antitoxin
JFL60_RS02295 437437..437904 + 468 WP_011609926.1 GNAT family N-acetyltransferase -
JFL60_RS02300 438665..438925 - 261 Protein_443 hemophilus-specific protein -
JFL60_RS02305 439012..439458 - 447 WP_011609888.1 hypothetical protein -
JFL60_RS02310 439676..440008 - 333 WP_011609887.1 hypothetical protein -
JFL60_RS02315 440161..440298 - 138 WP_157856877.1 hypothetical protein -
JFL60_RS02320 440379..441026 - 648 WP_198986231.1 DUF3560 domain-containing protein -
JFL60_RS02325 441200..441493 - 294 WP_165942798.1 hypothetical protein -
JFL60_RS02330 441635..441949 - 315 WP_198986233.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(3-86)


Sequences

Toxin        


Download         Length: 79 a.a.        Molecular weight: 8873.59 Da        Isoelectric Point: 10.4575

>T184700 WP_011609928.1 NZ_CP066567:436798-437034 [Histophilus somni]
MNLYLQKQVSQDIKRRIAPCFTVIDENKRILGYYTLASTSIPLVSLPENLKKKLPRYPSVPAVLLGRLAVDKQVSIFI

Download         Length: 237 bp

>T184700 NZ_CP087784:435251-435523 [Moraxella bovis]
GTGGCTAAACGTAGTTTTGAAATGGGCAATCCCTTTAAAAGGGATTTAAAAAAGCATTATTTGGCATTGATTGGCGAAGC
GTGGACGGAAGTGTCTGATTGCTTGTTAAATGCCAAACCCATACCTCAAAAATACCAAGACCACCCATTGCAAGGCGATT
GGGTGGGGTTTAGAGATTGTCATATCAAGCCTGATTTGGTGCTAATTTATAAAATAAATGATGAAGCGGTGGAATTACAT
CGGCTTGCCACGCATAGCGAGTTGTTTGGTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9906.35 Da        Isoelectric Point: 5.6388

>AT184700 WP_011609927.1 NZ_CP066567:437172-437435 [Histophilus somni]
MRTAAINLRVQPKQRDLIDYAASLLGKTRSDFMLDVACTYAQNVILDRTVFQLDEGKFNHFIEVLEQPNLPNAGLEKLMA
THSPWES

Download         Length: 264 bp

>AT184700 NZ_CP087784:434965-435258 [Moraxella bovis]
ATGAGCCACACCAATTTTAATATGCGATTAGACAACGACCTACGCCAAAAAGCCTATCCTGTGCTAGAACAATACGGCTT
GACTCCAAGCCAAGCAGTGCGGATGTTTTTTAATCAAATCGCCCAAACAGGCAAAGTGCCATTGTCTTTTGATTGGGGGC
AGTCGCATACGCTTAGTAGCAATGGCGAAAAGCTGTTGCGTGAGAGTATTCAAGCTTTTGAAAATGGCGAAACCGAGCGA
TTTGATAGCTTAGATGAGTTAAATCAAGCAATGGCGGAGATTGCTCGTGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References