Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4113394..4114054 Replicon chromosome
Accession NZ_CP066552
Organism Pectobacterium carotovorum strain 2A

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JFY74_RS18295 Protein ID WP_198997474.1
Coordinates 4113394..4113807 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag JFY74_RS18300 Protein ID WP_198997475.1
Coordinates 4113788..4114054 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JFY74_RS18275 4109090..4109989 - 900 WP_198997471.1 site-specific tyrosine recombinase XerD -
JFY74_RS18280 4110301..4111629 + 1329 WP_103861399.1 MHS family MFS transporter -
JFY74_RS18285 4111791..4112309 + 519 WP_198997472.1 flavodoxin FldB -
JFY74_RS18290 4112390..4113325 - 936 WP_198997473.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
JFY74_RS18295 4113394..4113807 - 414 WP_198997474.1 protein YgfX Toxin
JFY74_RS18300 4113788..4114054 - 267 WP_198997475.1 FAD assembly factor SdhE Antitoxin
JFY74_RS18305 4114290..4115291 + 1002 WP_198997476.1 tRNA-modifying protein YgfZ -
JFY74_RS18310 4115346..4115993 - 648 WP_116167200.1 hemolysin III family protein -
JFY74_RS18315 4116272..4116880 + 609 WP_095701613.1 HD domain-containing protein -
JFY74_RS18320 4116935..4117939 + 1005 WP_198997477.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16297.23 Da        Isoelectric Point: 10.5525

>T184661 WP_198997474.1 NZ_CP066552:c4113807-4113394 [Pectobacterium carotovorum]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNAKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR

Download         Length: 414 bp

>T184661 NZ_CP087765:c1687584-1687192 [Moraxella bovis]
ATGAAATATTTGCTGGACACCAATGCAGTCATTGCGATTTTGAATGCCAGTGAACGATTTTTGACCACGCTAGAACGGCA
TAAAGAGCGTGAAATTGCCATCTCGTCAATTGTTTTGTCGGAGCTGTATTATGGGGCGTACAAAAGCCAAAAAACCGCCC
AAAACCTTGAAAAAATCAATCTACTACCCTTTGAAGTGTTGCAATTTAATTCACAGGACGCTGATAAGGCTGGCGAAATT
GGTGCAACCCTAGAAAGGCGTGGCACACCCATTGGTTTTTATGACACGCTGATTGCAGGGCAAGCGATTGCCAATGATTT
GATTGTTATTACTGACAATGTGCGAGAATTTCTCCGAGTGGACGGTTTGCAAATTGAAAATTGGTTAAAATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10516.90 Da        Isoelectric Point: 5.1244

>AT184661 WP_198997475.1 NZ_CP066552:c4114054-4113788 [Pectobacterium carotovorum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELRHMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT184661 NZ_CP087765:c1687844-1687581 [Moraxella bovis]
ATGCGCCAAACTGCCACCGCAAAATTATTTTGGACTGGCAACAGTCAAGCCGTTCGCTTACCCAAAGCCTTTCGTTTTGA
AGGCACGGAAGTGCGTATCAAAAAACAAGGACGACAAGTGATTATTGAGCCAGCAGAGACCCAAGATTGGGCGTGGCTGG
ACAAATTGCGAGCAATGCCAAAAGATGACAGTTTTGAAGAAGCCATTTTGGAAGGTCGCCAAAATTTAAAAGCCGATGAA
CGAGATTGGGGTGCATTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References