Detailed information of TA system TA184661

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 4113394..4114054
• Replicon: chromosome
• Accession: NZ_CP066552
• Organism: Pectobacterium carotovorum strain 2A

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: JFY74_RS18295
• Protein ID: WP_198997474.1
• Coordinates: 4113394..4113807 (-)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: JFY74_RS18300
• Protein ID: WP_198997475.1
• Coordinates: 4113788..4114054 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JFY74_RS18275	4109090..4109989	-	900	WP_198997471.1	site-specific tyrosine recombinase XerD	-
JFY74_RS18280	4110301..4111629	+	1329	WP_103861399.1	MHS family MFS transporter	-
JFY74_RS18285	4111791..4112309	+	519	WP_198997472.1	flavodoxin FldB	-
JFY74_RS18290	4112390..4113325	-	936	WP_198997473.1	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	-
JFY74_RS18295	4113394..4113807	-	414	WP_198997474.1	protein YgfX	Toxin
JFY74_RS18300	4113788..4114054	-	267	WP_198997475.1	FAD assembly factor SdhE	Antitoxin
JFY74_RS18305	4114290..4115291	+	1002	WP_198997476.1	tRNA-modifying protein YgfZ	-
JFY74_RS18310	4115346..4115993	-	648	WP_116167200.1	hemolysin III family protein	-
JFY74_RS18315	4116272..4116880	+	609	WP_095701613.1	HD domain-containing protein	-
JFY74_RS18320	4116935..4117939	+	1005	WP_198997477.1	LacI family DNA-binding transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 16297.23 Da
• Isoelectric Point: 10.5525

>T184661 WP_198997474.1 NZ_CP066552:c4113807-4113394 [Pectobacterium carotovorum]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNAKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR

Nucleotide

• Length: 414 bp

>T184661 NZ_CP087765:c1687584-1687192 [Moraxella bovis]
ATGAAATATTTGCTGGACACCAATGCAGTCATTGCGATTTTGAATGCCAGTGAACGATTTTTGACCACGCTAGAACGGCA
TAAAGAGCGTGAAATTGCCATCTCGTCAATTGTTTTGTCGGAGCTGTATTATGGGGCGTACAAAAGCCAAAAAACCGCCC
AAAACCTTGAAAAAATCAATCTACTACCCTTTGAAGTGTTGCAATTTAATTCACAGGACGCTGATAAGGCTGGCGAAATT
GGTGCAACCCTAGAAAGGCGTGGCACACCCATTGGTTTTTATGACACGCTGATTGCAGGGCAAGCGATTGCCAATGATTT
GATTGTTATTACTGACAATGTGCGAGAATTTCTCCGAGTGGACGGTTTGCAAATTGAAAATTGGTTAAAATAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10516.90 Da
• Isoelectric Point: 5.1244

>AT184661 WP_198997475.1 NZ_CP066552:c4114054-4113788 [Pectobacterium carotovorum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELRHMISLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT184661 NZ_CP087765:c1687844-1687581 [Moraxella bovis]
ATGCGCCAAACTGCCACCGCAAAATTATTTTGGACTGGCAACAGTCAAGCCGTTCGCTTACCCAAAGCCTTTCGTTTTGA
AGGCACGGAAGTGCGTATCAAAAAACAAGGACGACAAGTGATTATTGAGCCAGCAGAGACCCAAGATTGGGCGTGGCTGG
ACAAATTGCGAGCAATGCCAAAAGATGACAGTTTTGAAGAAGCCATTTTGGAAGGTCGCCAAAATTTAAAAGCCGATGAA
CGAGATTGGGGTGCATTTGAATGA