184660

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 3788365..3789107 Replicon chromosome
Accession NZ_CP066552
Organism Pectobacterium carotovorum strain 2A

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag JFY74_RS16985 Protein ID WP_198997322.1
Coordinates 3788365..3788844 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag JFY74_RS16990 Protein ID WP_198997323.1
Coordinates 3788835..3789107 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JFY74_RS16925 3783458..3783811 - 354 WP_198997318.1 DUF1493 family protein -
JFY74_RS16930 3783796..3784266 - 471 WP_039491054.1 hypothetical protein -
JFY74_RS16935 3784396..3784647 + 252 WP_039491056.1 prevent-host-death protein -
JFY74_RS16940 3784637..3784792 + 156 Protein_3306 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
JFY74_RS16945 3784998..3785582 - 585 WP_198997319.1 Fic family protein -
JFY74_RS16950 3785575..3786066 - 492 WP_198997320.1 helix-turn-helix domain-containing protein -
JFY74_RS16955 3786370..3786636 + 267 WP_039355529.1 DUF1778 domain-containing protein -
JFY74_RS16960 3786638..3787153 + 516 WP_198997321.1 GNAT family N-acetyltransferase -
JFY74_RS16965 3787358..3787597 + 240 WP_039351585.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
JFY74_RS16970 3787597..3787884 + 288 WP_039351583.1 type II toxin-antitoxin system RelE/ParE family toxin -
JFY74_RS16975 3787903..3788109 + 207 Protein_3313 hypothetical protein -
JFY74_RS16980 3788105..3788260 + 156 Protein_3314 integrase arm-type DNA-binding domain-containing protein -
JFY74_RS16985 3788365..3788844 - 480 WP_198997322.1 GNAT family N-acetyltransferase Toxin
JFY74_RS16990 3788835..3789107 - 273 WP_198997323.1 DUF1778 domain-containing protein Antitoxin
JFY74_RS16995 3789503..3789709 + 207 WP_198999124.1 hypothetical protein -
JFY74_RS17000 3789829..3790968 - 1140 WP_010681611.1 glycoside hydrolase family 88 protein -
JFY74_RS17005 3791012..3792571 - 1560 WP_198997324.1 MFS transporter -
JFY74_RS17010 3792874..3793764 - 891 WP_198997325.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-146)

Antitoxin

Vibrio phage ICP1, Orf50

(10-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17462.18 Da        Isoelectric Point: 9.5963

>T184660 WP_198997322.1 NZ_CP066552:c3788844-3788365 [Pectobacterium carotovorum]
VGIMAPELLLPQHAVVDFRSSEPSLDDWLKRKALKNQTIGASRTFVVCESGGNQVIGFYALATGSVQRQSVSGALRRNMP
DLLPVLVLGRLAVDERYQRRGIGAGLLKDATLRSRQVAEQVGTKALLVHALSEEAKDFYLHWGFTPSEIQPSALLLPLW

Download         Length: 480 bp

>T184660 NZ_CP087765:1449514-1449774 [Moraxella bovis]
ATTGAGGCCTTATTTGTAGCATTAGGGGCGGACATCTCTGAGCGAGCAGGTTCACGCATGGCTGTGGCGCTAAACGGGCA
AGTCATGGTTTTTCATCGCCCACACCCAAGCCCAAATACTGACAAAAGTGCGGTTATGAGCATTAGAAAATGGCTTGATG
GCATGGGTATCACACCATTAGATGACGACAGCCAAACAGACGAATACGCAGACAAACAAACCGACGAACAGGAGCAGACT
CATGAACACAATGACAATTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10241.70 Da        Isoelectric Point: 4.8896

>AT184660 WP_198997323.1 NZ_CP066552:c3789107-3788835 [Pectobacterium carotovorum]
VRTEAKEAPINIRAKSSQRELIDVAAKLLSKSRTDFILEAACREAEEVLLDQRLFLVDDSQFNAFITALEKPVATNERLQ
ALLDRKSPWE

Download         Length: 273 bp

>AT184660 NZ_CP087765:1449755-1450090 [Moraxella bovis]
ATGAACACAATGACAATTAACAATCATAAAGCCTTAATCACTTTTGACAGTGAGTTAGGACTGTTTCGTGGGGAGTTTAT
CGGATTAAATGGCGGGGCAGATTTTTATGCTGACAGCGTAGATGGTCTCAATGAACAAGGGGCTTTATCCCTGCAAGCCT
TTTTAGATGTATGTCAAGAACAGGGCATTAGCCCTTATCAGTCGTACAGTGGCAAATTTGTCACACGCCTACCCAAAGAG
TTACATCAAAAAATCGCAGAAACTGCTACCGCCAAGGGTATTAGCCTAAACCAGTGGATTAATGAAACACTCAGCCGTGA
AGTTGGCTTTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References