Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-RelB |
Location | 3787358..3787884 | Replicon | chromosome |
Accession | NZ_CP066552 | ||
Organism | Pectobacterium carotovorum strain 2A |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A7V8IHI4 |
Locus tag | JFY74_RS16970 | Protein ID | WP_039351583.1 |
Coordinates | 3787597..3787884 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A7V8L5M4 |
Locus tag | JFY74_RS16965 | Protein ID | WP_039351585.1 |
Coordinates | 3787358..3787597 (+) | Length | 80 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JFY74_RS16910 | 3782378..3782623 | + | 246 | WP_039491049.1 | CopG family ribbon-helix-helix protein | - |
JFY74_RS16915 | 3782613..3782897 | + | 285 | WP_039491050.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
JFY74_RS16920 | 3782956..3783315 | + | 360 | WP_198997317.1 | hypothetical protein | - |
JFY74_RS16925 | 3783458..3783811 | - | 354 | WP_198997318.1 | DUF1493 family protein | - |
JFY74_RS16930 | 3783796..3784266 | - | 471 | WP_039491054.1 | hypothetical protein | - |
JFY74_RS16935 | 3784396..3784647 | + | 252 | WP_039491056.1 | prevent-host-death protein | - |
JFY74_RS16940 | 3784637..3784792 | + | 156 | Protein_3306 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | - |
JFY74_RS16945 | 3784998..3785582 | - | 585 | WP_198997319.1 | Fic family protein | - |
JFY74_RS16950 | 3785575..3786066 | - | 492 | WP_198997320.1 | helix-turn-helix domain-containing protein | - |
JFY74_RS16955 | 3786370..3786636 | + | 267 | WP_039355529.1 | DUF1778 domain-containing protein | - |
JFY74_RS16960 | 3786638..3787153 | + | 516 | WP_198997321.1 | GNAT family N-acetyltransferase | - |
JFY74_RS16965 | 3787358..3787597 | + | 240 | WP_039351585.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
JFY74_RS16970 | 3787597..3787884 | + | 288 | WP_039351583.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
JFY74_RS16975 | 3787903..3788109 | + | 207 | Protein_3313 | hypothetical protein | - |
JFY74_RS16980 | 3788105..3788260 | + | 156 | Protein_3314 | integrase arm-type DNA-binding domain-containing protein | - |
JFY74_RS16985 | 3788365..3788844 | - | 480 | WP_198997322.1 | GNAT family N-acetyltransferase | - |
JFY74_RS16990 | 3788835..3789107 | - | 273 | WP_198997323.1 | DUF1778 domain-containing protein | - |
JFY74_RS16995 | 3789503..3789709 | + | 207 | WP_198999124.1 | hypothetical protein | - |
JFY74_RS17000 | 3789829..3790968 | - | 1140 | WP_010681611.1 | glycoside hydrolase family 88 protein | - |
JFY74_RS17005 | 3791012..3792571 | - | 1560 | WP_198997324.1 | MFS transporter | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11316.16 Da Isoelectric Point: 10.1960
>T184659 WP_039351583.1 NZ_CP066552:3787597-3787884 [Pectobacterium carotovorum]
MSYFLDFDERALKEWRKLGETIRNQFKKKLADILDAPRIEANKLRSMPDCYKIKLRSAGYRLVYQVQDEKVVVFVVSVGK
RERSEAYDDAIKRLR
MSYFLDFDERALKEWRKLGETIRNQFKKKLADILDAPRIEANKLRSMPDCYKIKLRSAGYRLVYQVQDEKVVVFVVSVGK
RERSEAYDDAIKRLR
Download Length: 288 bp
>T184659 NZ_CP087765:c702069-701887 [Moraxella bovis]
ATGAAGTATTCAGAGTTTCAAAGGTGGCTATTGGCACAAGGGGCAACGGTAAACAAGCAAGGCGGTAAAGGCTCGCACCG
TAAAGTTACCCTAAATGGCAAAACCACCACTTTCCCTTATCACGGCAGTAAAGAGATTGGGGAAGGACTAAGAAAGAAAA
TTTTAAAAGACTTGGATTTATAG
ATGAAGTATTCAGAGTTTCAAAGGTGGCTATTGGCACAAGGGGCAACGGTAAACAAGCAAGGCGGTAAAGGCTCGCACCG
TAAAGTTACCCTAAATGGCAAAACCACCACTTTCCCTTATCACGGCAGTAAAGAGATTGGGGAAGGACTAAGAAAGAAAA
TTTTAAAAGACTTGGATTTATAG
Antitoxin
Download Length: 80 a.a. Molecular weight: 9051.37 Da Isoelectric Point: 4.5112
>AT184659 WP_039351585.1 NZ_CP066552:3787358-3787597 [Pectobacterium carotovorum]
MGSINLRIDDDLKTRSYAALEKLGVTPSEALRLTLEYIAENERLPFKQALLSDEDAELIEIVRERLRNPKPVRVTLDDL
MGSINLRIDDDLKTRSYAALEKLGVTPSEALRLTLEYIAENERLPFKQALLSDEDAELIEIVRERLRNPKPVRVTLDDL
Download Length: 240 bp
>AT184659 NZ_CP087765:c701825-701412 [Moraxella bovis]
ATGTACTATCCTGCTACTTTTACCCCTGATACCAATGATACTTTTTTGGTGGCGTTTCGTGATATTCCCGAAGCGGTGGG
CGTGGGTGAAACCTTTGAAATCGCCTACCAATCCGCCCTTGACGGCTTAGAAACGGCATTTAGCATCTATATGGACGAAC
GCAAGCCAATCCCCGCCCCCAGTGAGCTGTCTGACGGCGAACACGCCATTTATTTGCCTGTGGCGGTACAGACCAAACTT
GCCTTATATCACGAAATGCTAGCCCAAGGCGTTACTAAGGCGGAGCTGGCTCGCCGTCTGTCTGTCAATCAAAAACAAAT
TGATAGACTTTGGGACGTGAGCCACTCCACCAAATTAGAATTTTTGGAAAAGGCGTTTAGCGTGCTAGGCAAACGCCTAT
CCCTAGCCATTTAA
ATGTACTATCCTGCTACTTTTACCCCTGATACCAATGATACTTTTTTGGTGGCGTTTCGTGATATTCCCGAAGCGGTGGG
CGTGGGTGAAACCTTTGAAATCGCCTACCAATCCGCCCTTGACGGCTTAGAAACGGCATTTAGCATCTATATGGACGAAC
GCAAGCCAATCCCCGCCCCCAGTGAGCTGTCTGACGGCGAACACGCCATTTATTTGCCTGTGGCGGTACAGACCAAACTT
GCCTTATATCACGAAATGCTAGCCCAAGGCGTTACTAAGGCGGAGCTGGCTCGCCGTCTGTCTGTCAATCAAAAACAAAT
TGATAGACTTTGGGACGTGAGCCACTCCACCAAATTAGAATTTTTGGAAAAGGCGTTTAGCGTGCTAGGCAAACGCCTAT
CCCTAGCCATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7V8IHI4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7V8L5M4 |