Detailed information of TA system TA184657

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 3212822..3213375
• Replicon: chromosome
• Accession: NZ_CP066552
• Organism: Pectobacterium carotovorum strain 2A

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: -
• Locus tag: JFY74_RS14325
• Protein ID: WP_198997057.1
• Coordinates: 3213061..3213375 (+)
• Length: 105 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: -
• Locus tag: JFY74_RS14320
• Protein ID: WP_198997056.1
• Coordinates: 3212822..3213058 (+)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JFY74_RS14295	3208303..3208686	+	384	Protein_2805	hypothetical protein	-
JFY74_RS14305	3208980..3209126	-	147	WP_198997054.1	hypothetical protein	-
JFY74_RS14310	3210424..3211062	-	639	WP_198997055.1	hypothetical protein	-
JFY74_RS14315	3211637..3212503	+	867	Protein_2808	DUF1738 domain-containing protein	-
JFY74_RS14320	3212822..3213058	+	237	WP_198997056.1	type II toxin-antitoxin system CcdA family antitoxin	Antitoxin
JFY74_RS14325	3213061..3213375	+	315	WP_198997057.1	CcdB family protein	Toxin
JFY74_RS14335	3214302..3214550	+	249	Protein_2811	LysR family transcriptional regulator	-
JFY74_RS14340	3214961..3215227	+	267	WP_198997058.1	anti-adapter protein IraP	-
JFY74_RS14345	3215392..3216804	-	1413	WP_198997059.1	D-serine/D-alanine/glycine transporter	-
JFY74_RS14355	3217400..3217990	-	591	WP_198997060.1	flavin reductase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin CcdB (2-103)

Antitoxin

• Post-segregation antitoxin CcdA (9-78)

Sequences

Toxin

Protein

• Length: 105 a.a.
• Molecular weight: 11549.50 Da
• Isoelectric Point: 7.9859

>T184657 WP_198997057.1 NZ_CP066552:3213061-3213375 [Pectobacterium carotovorum]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLIPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRTQVKAAIDFLIDGF

Nucleotide

• Length: 315 bp

>T184657 NZ_CP087765:560190-560432 [Moraxella bovis]
ATGAATTATAGCGAATTTCGCCAAAACCTAGCGTCCGCCCTTGATTATGTTCAAGACAGCCATGCCCCTGTGATTGTCAA
ACGTGGCAAACATTCTGCGGTGGTGATTAGTCTTGATGAATATAATGCTTTTAAAGAAACAGATTATCTATTGTCAAACC
CTGCTAATGCCGAACACCTTATGCGTGGCGTGCAAGCGGTAAAAAATCGTCAACTTACCCAAAGGGATTTGATTGAGGAT
TAG

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8954.99 Da
• Isoelectric Point: 6.2181

>AT184657 WP_198997056.1 NZ_CP066552:3212822-3213058 [Pectobacterium carotovorum]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLTTALDAELRYHEAKKWQEENREALAALNHFHDEQGCFSDEYRAF

Nucleotide

• Length: 237 bp

>AT184657 NZ_CP087765:560422-560679 [Moraxella bovis]
TTGAGGATTAGATGGTTTGATGAGGTATGGGAGGATTATTTGTATTGGCAAAGCCAAGATAAGAAAACCATAAAACGTAT
TAATACCTTGATTAAGGATTGCAGACGAGACCCTTTTGACGGTATCGGCAAACCCGAACCATTAAAATATAACCTAACAG
GCTACTGGTTAAGACGCATTGATGATGCCAACCGCTTGGTTTATTGTTGCGAAAGTGAAACACTCATCATTTCATGCCGT
CATCATTATGAGGCTTAA