Detailed information of TA system TA184651

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 587711..588238
• Replicon: chromosome
• Accession: NZ_CP066552
• Organism: Pectobacterium carotovorum strain 2A

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JFY74_RS02660
• Protein ID: WP_198998054.1
• Coordinates: 587963..588238 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JFY74_RS02655
• Protein ID: WP_198998053.1
• Coordinates: 587711..587959 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JFY74_RS02645	583921..587169	+	3249	WP_198998052.1	DEAD/DEAH box helicase family protein	-
JFY74_RS02650	587261..587550	+	290	Protein_508	virulence RhuM family protein	-
JFY74_RS02655	587711..587959	+	249	WP_198998053.1	ribbon-helix-helix domain-containing protein	Antitoxin
JFY74_RS02660	587963..588238	+	276	WP_198998054.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JFY74_RS02665	588286..588798	+	513	WP_198998055.1	AAA family ATPase	-
JFY74_RS02670	588843..590429	-	1587	WP_198998056.1	RNA repair transcriptional activator RtcR	-
JFY74_RS02675	590630..591856	+	1227	WP_198999026.1	RtcB family protein	-
JFY74_RS02680	591861..592652	+	792	WP_198998057.1	nucleotidyltransferase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	577637..588798	11161

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-43)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 11065.35 Da
• Isoelectric Point: 5.1349

>T184651 WP_198998054.1 NZ_CP066552:587963-588238 [Pectobacterium carotovorum]
MEIRWTQKAQDGLERIYGFFSQYSRQHADEVLDRLIIGTTGLADHLRIGVSQTRYEPREVRKILFDDYDVHYEIQHDTIY
IVDLWYTREDR

Nucleotide

• Length: 276 bp

>T184651 NZ_CP087761:975817-976122 [Lactobacillus gasseri]
ATGGCTCAAATTAACTACACTCCTCAATTTAAGCGAGATTATAAGAAGCTTAAAAGAAAACATTATGATTTGAATAAATT
AAAAAATGTCATTCAATTACTTATTGACGAAAAATTTAAAATTCTTGTTGATAAATATGATGACCATCAACTAAAAGGTT
CTTTAAGGTCACTACGTGCATTACATGTTGAGCATAATAAAGCTGGTAATTGGATTTTAGTTTATAAAATTCATAGCGGC
AATTTAGAACTGTTAACCATCGACTTGGTTTCTACTGGTTCCCACGATCATACTTATAGAACATAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 8985.25 Da
• Isoelectric Point: 6.4653

>AT184651 WP_198998053.1 NZ_CP066552:587711-587959 [Pectobacterium carotovorum]
MGQSAKQTISAQIPAELAAAVESLAIELDRSKSWVIKEALTAMIEERERRHQQVLKGLADVDTGRVVSHADVIDFANKLK
NS

Nucleotide

• Length: 249 bp

>AT184651 NZ_CP087761:975542-975817 [Lactobacillus gasseri]
ATGACAACTACCGTAAGTTTAAGATTACCAGAAGATTTAAAGAAACAAGCAACAGATGTATTCAACGAATACGGTCTCGA
TTGGTCATCTGCAATGCGAATGATCTTAACTCAAGTCGTAAGTGAAAATGCAATTCCTGTTAATTTACATAGATATTCTG
AAATTTCTCCTTCGATGAAATCAAATATTGATAGGTCACTTCAAGAATACAAAGCAGGAAATTATAAAACCACAAACTCA
GTAAAAGAGCTATTTGAGGAGTTAGATAAAGACTAA