Detailed information of TA system TA184649

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 174693..176133
• Replicon: chromosome
• Accession: NZ_CP066552
• Organism: Pectobacterium carotovorum strain 2A

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: JFY74_RS00775
• Protein ID: WP_198997845.1
• Coordinates: 175246..176133 (+)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: A0A7T5UAJ1
• Locus tag: JFY74_RS00770
• Protein ID: WP_039490190.1
• Coordinates: 174693..175217 (+)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JFY74_RS00760	169983..171875	+	1893	WP_198997843.1	hypothetical protein	-
JFY74_RS00765	171894..174374	+	2481	WP_198997844.1	restriction endonuclease-like protein	-
JFY74_RS00770	174693..175217	+	525	WP_039490190.1	hypothetical protein	Antitoxin
JFY74_RS00775	175246..176133	+	888	WP_198997845.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
JFY74_RS00780	176227..177090	-	864	WP_010300687.1	YicC family protein	-
JFY74_RS00785	177189..178097	-	909	WP_198997846.1	LysR family transcriptional regulator	-
JFY74_RS00790	178311..179258	-	948	WP_039508432.1	isoaspartyl peptidase/L-asparaginase	-
JFY74_RS00795	179319..180140	-	822	WP_198997847.1	M55 family metallopeptidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (36-265)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 33992.88 Da
• Isoelectric Point: 5.6716

>T184649 WP_198997845.1 NZ_CP066552:175246-176133 [Pectobacterium carotovorum]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIMDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFQPSAFE
GLESEIQTYIQNKYETEVWVNKPSGAQQGDTVSWKISIVKEANHPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWAYVQGEVHTIASELLNDGTPKNPFDMG

Nucleotide

• Length: 888 bp

>T184649 NZ_CP087719:4994585-4994995 [Roseomonas sp. OT10]
GTGACGCCGCGCTACCTGCTCGACACCAACCTGTGCATCCGCGTGCTGCGCGACCGGCCGGCGGGCCTGCGGGAGCGCTT
CAATGCCGAGGCCGAGGCGCTCTGCACCTCCGAGGTGGTGCGCTACGAGCTGCTGTACGGCGCGGAGCGCTCGGCCCGGC
CGGCGGAGGTGCGGCGGGAGGTGGAGCGCTTTGCCGCCCGGCTGGCCGTGCTGCCGTTCGACGACGCGGCCGCCGCCCAC
ACGGCGCAGATCCGCGCGGAGCTGGAGCGCCAGGGCGCGGTGATCGGCCCCTATGACCTCATGATCGCCGGGCAGGCGCG
CAGCCGTGGGCTGGTGGTCGTGACCGGCAACCTGGGCGAGTTCGGCCGGGTGGCGGGGCTGCGTTGCGAGGATTGGCTGG
CGGGATCGTGA

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19358.53 Da
• Isoelectric Point: 9.0504

>AT184649 WP_039490190.1 NZ_CP066552:174693-175217 [Pectobacterium carotovorum]
MAKSDELLNALAKSVNAGGGIHSVTELAFMQGVPCDPAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIELTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Nucleotide

• Length: 525 bp

>AT184649 NZ_CP087719:4994364-4994588 [Roseomonas sp. OT10]
ATGCCAACCCGCACCACCCTGTTCCTGTCCAACCGGTCCCAGGCCGTGCGCCTGCCGAAGGGCGTCGCCTTCGAAGCCGG
CGTGCGCGAGGTGGTCATCCTGCGCGACGGGGTCCGCCGCGTGATCGCCCCGGCCGACGCGGCGTGGGACGACTTCTTCG
CCGCCCCCGGTGTCGATCTCGGGGAACGGCAACAGCCGCCGATGCAGGACCGCGAGGCCCTGTGA

Structures

Antitoxin

• AlphaFold DB: A0A7T5UAJ1