Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 2410308..2410836 Replicon chromosome
Accession NZ_CP066546
Organism Pseudomonas chlororaphis subsp. aureofaciens strain SPS-41

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JE032_RS11065 Protein ID WP_198920061.1
Coordinates 2410308..2410613 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JE032_RS11070 Protein ID WP_096373267.1
Coordinates 2410597..2410836 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JE032_RS11040 2405428..2405970 + 543 WP_007922237.1 XRE family transcriptional regulator -
JE032_RS11045 2406295..2407314 - 1020 WP_038630801.1 DUF4917 family protein -
JE032_RS11050 2407472..2408620 + 1149 WP_198919854.1 L-threonine dehydrogenase -
JE032_RS11055 2408816..2409388 + 573 WP_198919855.1 TetR/AcrR family transcriptional regulator -
JE032_RS11060 2409608..2410279 + 672 WP_198919856.1 epimerase -
JE032_RS11065 2410308..2410613 - 306 WP_198920061.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JE032_RS11070 2410597..2410836 - 240 WP_096373267.1 CopG family ribbon-helix-helix protein Antitoxin
JE032_RS11075 2410973..2411389 + 417 WP_198919857.1 fosfomycin resistance glutathione transferase -
JE032_RS11080 2411517..2412155 + 639 WP_016702101.1 LysE family translocator -
JE032_RS11085 2412267..2413607 + 1341 WP_016702102.1 sensor domain-containing diguanylate cyclase -
JE032_RS11090 2413747..2414271 + 525 WP_009047451.1 DUF4142 domain-containing protein -
JE032_RS11095 2414365..2415255 - 891 WP_198919858.1 phosphotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11695.35 Da        Isoelectric Point: 10.8916

>T184643 WP_198920061.1 NZ_CP066546:c2410613-2410308 [Pseudomonas chlororaphis subsp. aureofaciens]
MARHVEWLRSALKNLDDEAAYIAQDSPQAAAEFVKAILSSIQHLSRFPASGREGRLPGTREWVVPNRPYLIPYRVRQGHL
QILRIFHTRRLPPAGWQDDRQ

Download         Length: 306 bp

>T184643 NZ_CP087718:1232-1519 [Acinetobacter pittii]
ATGGAACAGTATTTTGAATGGGATGAGGCTAAGAATCGAAAGAATCAGAAAAAGCATGATATCTCTTTCGAAACTGCAAG
CCTTGTTTTTGAAGATCCATTACGGATCTCAATCCAAGACAGACATACCGATGGTGAAGAACGTTGGCAAACCATTGGAC
GAGTTAAAGGCGTACTAATGTTATTGGTGGCTCACACCATTTTTGATGAAGATGACTGTGAAATCATACGAATCATTAGT
GCAAGGCAAGTGACTAAAGCGGAGCGAAACAAATATGAGCATGGTTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8692.82 Da        Isoelectric Point: 4.7672

>AT184643 WP_096373267.1 NZ_CP066546:c2410836-2410597 [Pseudomonas chlororaphis subsp. aureofaciens]
MSVMSLRLPDDVANSLAHLAKATGRSKSFLAVDALREYLAREAWQIDEIQKALTEAEAGDFASAEELDNVLTKWTGKAR

Download         Length: 240 bp

>AT184643 NZ_CP087718:1506-1820 [Acinetobacter pittii]
ATGAGCATGGTTAGATACTCACGCAAAGAGCTGAATGAGAAATTTGTTGAGAAGCAAGATGCTGAAATTCAACGCTTGCT
TGCTAAAGGCACGGTTCCTGATGATCAGCTAGATCTATCAGATATTCCTGAAATTACCGATTGGAGCAGTGCTGTACGCC
AAAATCAATTTTACCGCCCAGTGAAGCAACAAACTTCAATTCGGTTAGATGCTGATGTACTTGCTTGGTTCAAAGCACAA
GGCAAAGGTTATCAAACACGAATGAATGAAATTTTACGGGATGCTATGCTGAAAGAATTAAAAAATCATCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References