Detailed information of TA system TA184372

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /DUF1778(antitoxin)
• Location: 4418348..4419144
• Replicon: chromosome
• Accession: NZ_CP066369
• Organism: Shewanella putrefaciens strain CGMCC-1.6515

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JFT56_RS19170
• Protein ID: WP_198781553.1
• Coordinates: 4418348..4418878 (-)
• Length: 177 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JFT56_RS19175
• Protein ID: WP_198781554.1
• Coordinates: 4418875..4419144 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JFT56_RS19155	4414241..4415008	-	768	WP_198781550.1	class I SAM-dependent methyltransferase	-
JFT56_RS19160	4415278..4416063	+	786	WP_198781551.1	hypothetical protein	-
JFT56_RS19165	4416929..4418134	-	1206	WP_198781552.1	hypothetical protein	-
JFT56_RS19170	4418348..4418878	-	531	WP_198781553.1	GNAT family N-acetyltransferase	Toxin
JFT56_RS19175	4418875..4419144	-	270	WP_198781554.1	DUF1778 domain-containing protein	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (96-155)

Antitoxin

• Vibrio phage ICP1, Orf50 (5-81)

Sequences

Toxin

Protein

• Length: 177 a.a.
• Molecular weight: 19665.90 Da
• Isoelectric Point: 8.6096

>T184372 WP_198781553.1 NZ_CP066369:c4418878-4418348 [Shewanella putrefaciens]
VSYSKTFKELDKSQHDRASFDCGEAELNDFIQTQAAKHMQAGISRTMVLPAATPLPNQKFPICSFYTIAPSSICRDTLPQ
AIGKKLPRYPIPVFLLAQLAVHKEFHGSGLGKASLIKALEYLWEINAHMRAYAIVVDCLTGQAESFYAKYGFEVLCEING
RVRMFIPMKTVGQLFT

Nucleotide

• Length: 531 bp

>T184372 NZ_CP087629:c5335969-5335586 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9814.22 Da
• Isoelectric Point: 4.7037

>AT184372 WP_198781554.1 NZ_CP066369:c4419144-4418875 [Shewanella putrefaciens]
MATARLDIRLDEEIKARAEKASALLGLKSLTEYVVRLMDEDATQVIAEHESVTVKADVFDQFILACDEAKAPNKALREAA
AFTKSGEFK

Nucleotide

• Length: 270 bp

>AT184372 NZ_CP087629:c5336211-5335969 [Klebsiella pneumoniae subsp. pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA